Publications by authors named "Namrata Bali"

Informal and unregulated work is the norm rather than the exception in emerging economies. This study was conducted in India where nine out of 10 women are occupied in informal, unregulated work, and are vulnerable to low-wages, exploitation, and interconnected cultural and social-economic injustices. The Self-Employed Women's Association (SEWA) and their education wing the Indian Academy of Self-Employed Women encourage their members to self-define as "self-employed workers" and facilitate identity-based worker education and leadership training.

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Type IIa receptor-like protein tyrosine phosphatases (RPTPs) are essential for neural development. They have cell adhesion molecule (CAM)-like extracellular domains that interact with cell-surface ligands and coreceptors. We identified the immunoglobulin superfamily CAM Sticks and Stones (Sns) as a new partner for the Type IIa RPTP Lar.

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The activity and/or localization of receptor tyrosine kinases and phosphatases are controlled by binding to cell-surface or secreted ligands. Identification of ligands for receptor tyrosine phosphatases (RPTPs) is essential for understanding their in vivo functions during development and disease. Here we describe a novel in vivo method to identify ligands and binding partners for RPTPs by staining live-dissected Drosophila embryos.

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We recently demonstrated that human C-reactive protein (CRP), expressed hepatically in transgenic mice (CRPtg), improved the outcome of experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis (MS). The liver is the primary site of CRP synthesis in humans and in CRPtg mice but is also expressed by both at low levels in the CNS. To determine if CNS expression of human CRP is sufficient to impact EAE, we generated neuronal CRP transgenic mice (nCRPtg) wherein human CRP expression is driven by the neuron-specific Ca(2+)/calmodulin-dependent protein kinase IIα (CaMKIIα) gene promoter.

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Article Synopsis
  • * MAO A/B knockout (KO) mice show heightened fear responses and increased eye-blink conditioning compared to normal mice, indicating cognitive changes related to abnormal neurotransmitter levels.
  • * These findings suggest that the chronic increase in monoamines due to the absence of MAOs leads to significant functional and cellular changes in learning and memory, positioning MAO A/B KO mice as a valuable model for studying related disorders.
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Progesterone (P4) and estradiol (E2) modulate neurogenesis and synaptic remodeling in the hippocampus during the rat estrous cycle and in response to deafferenting lesions, but little is known about the steroidal regulation of hippocampal progesterone receptors associated with these processes. We examined the neuronal expression of progesterone receptor membrane component-1 (Pgrmc1) and the classical progesterone receptor (Pgr), by in situ hybridization and immunohistochemistry. Pgr, a transcription factor, has been associated with synaptic remodeling and other major actions of P4, whereas Pgrmc1 is implicated in P4-dependent proliferation of adult neuroprogenitor cells and with rapid P4 effects on membranes.

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