Publications by authors named "Nami Takai"
Background: Chronic kidney disease (CKD) awareness could help prevent disease progression through modifiable risk factors. However, few patients with CKD are aware of their disease. We aimed to investigate the factors associated with CKD awareness and impact of CKD awareness on renal prognosis.
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- Patients who are immunosuppressed, like kidney transplant recipients, typically have lower antibody responses after SARS-CoV-2 vaccinations, but responses improve with more doses.
- In a study of Japanese kidney transplant patients, antibody positivity rates increased to 75.0% after the fourth dose and 81.5% after the fifth dose.
- Those who developed antibodies after their fourth vaccination had higher body mass index and better kidney function, suggesting that further doses are beneficial for improving immunity against COVID-19.
Post-renal-transplant patients have a relatively low antibody-acquisition rate following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccination. In this study, antibody titers were measured 5−6 months and 3 weeks to 3 months after the second and third SARS-CoV-2 mRNA vaccinations, respectively. Post-renal-transplant patients visiting our hospital who had received three SARS-CoV-2 mRNA vaccine doses were included in the study.
View Article and Find Full Text PDFImmunocompromised patients, especially those who undergo kidney transplantation, have lower antibody levels following SARS-CoV-2 mRNA vaccination. The situation of transplant treatment, such as transplant source and immunosuppressive drugs, is different in Japan than that in other countries. Therefore, it is necessary to clarify whether antibody acquisition rates differ between Japan and other countries.
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