Publications by authors named "Nami Kawaguchi"

Article Synopsis
  • The study explores the effects of Eucommia leaf extract (ELE) on obesity, glycolysis, and lipid metabolism in male rats, showing promising anti-obesity outcomes.
  • Both 5% ELE and ELE aroma treatments resulted in notable changes in metabolic markers, including increased mRNA levels for important metabolic genes in the liver.
  • The findings suggest that ELE enhances lipid metabolism and aerobic glycolysis, potentially aiding in the regulation of metabolic syndrome through the influence of brain-derived neurotrophic factor (BDNF).
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Leukemia inhibitory factor (LIF) is a cytokine involved in the survival and differentiation of the neural cells in the central and peripheral nervous systems. In the present study, we examined the effects of various neurotransmitter receptor agonists on LIF mRNA expression in cultured rat astrocytes, microglia and neurons to elucidate the cell types producing LIF and to clarify the neurotransmitter(s) regulating the mRNA expression. The results demonstrated that the expression of LIF mRNA was intensely induced by ATP in the cultured astrocytes.

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