Efficacy and Safety of Sinetrol-XPur on Weight and Body Fat Reduction in Overweight or Obese Adults: A 12-Week, Randomized, Double-Blind, Parallel, Placebo-Controlled Trial.

This study investigated the effect of Sinetrol-XPur on weight and body fat reduction in overweight or obese Korean participants. Among 100 overweight or obese participants enrolled in a 12-week randomized, double-blinded, controlled study, 86 participants completed the trial. Participants took either two Sinetrol-XPur tablets (450 mg per tablet) or two placebo tablets once a day.

Patellofemoral Chondromalacia Does Not Influence Radiographic and Clinical Outcomes following High Tibial Osteotomy.

Effect of patellofemoral (PF) chondromalacia on results of high tibial osteotomy (HTO) has not been identified. Therefore, the objective of the present study was to analyze the effect of PF chondromalacia on relatively short-term radiographic and clinical outcomes of HTO. Patients who underwent open wedge HTO (OWHTO) from February 2010 to January 2015 were enrolled.

Synergistic Neuroprotective Effect of and on Neuronal Cell Death and Scopolamine-Induced Cognitive Impairment in Rats.

Mild cognitive impairment (MCI) is considered as a transitional stage between aging and Alzheimer's disease. In the present study, we examined the protective effect of (SC) and (RF) on neuronal cell death in vitro and scopolamine-induced cognitive impairment in Sprague Dawley rats in vivo. A mixture of SC and RF extracts (SC+RF) significantly protected against hydrogen peroxide-induced PC12 neuronal cell death.

Correction to: Meniscal extrusion is positively correlated with the anatomical position changes of the meniscal anterior and posterior horns, following medial meniscal allograft transplantation.

The article Meniscal extrusion is positively correlated with the anatomical position changes of the meniscal anterior and posterior horns, following medial meniscal allograft transplantation.

Nonanatomic Horn Position Increases Risk of Early Graft Failures After Lateral Meniscal Allograft Transplantation.

Background: The cause of early graft failure within 1 year of meniscal allograft transplantation (MAT) remains unclear. The association of early failure with a nonanatomic horn position of the allograft after lateral MAT with the keyhole technique has never been evaluated.

Hypothesis: A nonanatomic horn position of an allograft would be a significant risk factor for a premature graft tear as compared with an anatomically positioned allograft.

Meniscal extrusion is positively correlated with the anatomical position changes of the meniscal anterior and posterior horns, following medial meniscal allograft transplantation.

Purpose: The purpose was to analyse the correlation between meniscal extrusion and position changes of the anterior horn and posterior horn after medial meniscal allograft transplantation.

Methods: Patients (n = 68) who underwent medial MAT were included. Anatomical positions of the anterior horn and posterior horn were measured, before and after surgery, using magnetic resonance images in the coronal and sagittal planes.

Does discoid lateral meniscus have inborn peripheral rim instability? Comparison between intact discoid lateral meniscus and normal lateral meniscus.

Introduction: Little is known about peripheral rim instability (PRI) of adult discoid lateral meniscus (DLM). We compared PRI of the intact DLM (iDLM) to those of intact normal lateral meniscus (LM) in adult patients and also investigated whether there was any association between PRI and DLM tears.

Materials And Methods: We investigated PRI in 17 DLMs and 60 normal LMs without tears during arthroscopic surgery for medial compartmental pathologies between June 2012 and October 2015.

Distinct extra-articular invasion patterns of diffuse pigmented villonodular synovitis/tenosynovial giant cell tumor in the knee joints.

Purpose: Pigmented villonodular synovitis (PVNS)/tenosynovial giant cell tumor (TGCT) is a benign, proliferative lesion of the synovium, the bursa, and the tendon sheath. Little is known about the anatomical distribution pattern of diffuse extra-articular PVNS/TGCT around the knee joint. In this retrospective study, anatomical distribution of PVNS/TGCT using magnetic resonance imaging (MRI) and arthroscopy was analyzed.

Mobile-bearing unicompartmental knee arthroplasty in old-aged patients demonstrates superior short-term clinical outcomes to open-wedge high tibial osteotomy in middle-aged patients with advanced isolated medial osteoarthritis.

Purpose: The aim of the present study was to compare the clinical outcomes of mobile-bearing unicompartmental knee arthroplasty (MB-UKA) and open-wedge high tibial osteotomy (OWHTO) for advanced isolated medial osteoarthritis (OA).

Methods: Patients with advanced medial compartment OA (Ahlbäck grade ≥ II) who underwent either MB-UKA with Oxford Knee or OWHTO were included. The minimum follow-up was two years.

Arthroscopic partial meniscectomy in young patients with symptomatic discoid lateral meniscus: an average 10-year follow-up study.

Introduction: The aim of this study is to evaluate mid-to-long-term clinical and radiological outcomes after an arthroscopic partial meniscectomy for symptomatic discoid lateral meniscus (DLM) in young patients and to determine whether degeneration of the residual meniscus and articular cartilage progresses during the follow-up period using magnetic resonance imaging (MRI).

Materials And Methods: We retrospectively reviewed patients aged ≤ 40 years at surgery who underwent arthroscopic partial meniscectomy for symptomatic DLM and were followed up for ≥ 5 years. Lysholm knee scores and reoperation rates were assessed as clinical outcomes.

Meniscal Extrusion Does Not Progress During the Midterm Follow-up Period After Lateral Meniscal Transplantation.

Background: Meniscal extrusion is related to degeneration of the native knee joint. However, the clinical effect of the phenomenon after meniscal allograft transplantation (MAT) has not been clearly identified. Purpose/Hypothesis: The purpose of this study was to evaluate the change in meniscal extrusion in both the coronal and sagittal planes after lateral MAT through the midterm follow-up period.

Long-term Survival Analysis of Meniscus Allograft Transplantation With Bone Fixation.

Purpose: To investigate the long-term clinical results and clinical survival rate of meniscus allograft transplantation (MAT) with bone fixation.

Methods: The inclusion criteria of this study were previous MAT with bone fixation technique in our institution and minimum follow-up duration of 8 years. Potential subjects were identified using the medical records and database that was prospectively collected from December 1996 to December 2005.

Prophylaxis for Venous Thromboembolism Following Total Knee Arthroplasty: A Survey of Korean Knee Surgeons.

Purpose: The purpose of this study is to provide information on the actual status and prevailing trend of prophylaxis for venous thromboembolism (VTE) following total knee arthroplasty (TKA) in South Korea.

Materials And Methods: The Korean Knee Society (KKS) developed a questionnaire with 6 clinical questions on VTE. The questionnaire was distributed to all members of KKS by both postal and online mail.

Magnetic Resonance Imaging Findings in Symptomatic Patients After Arthroscopic Partial Meniscectomy for Torn Discoid Lateral Meniscus.

Purpose: To evaluate the change in the thickness and width of the residual meniscus using magnetic resonance imaging (MRI) in patients who underwent arthroscopic partial meniscectomy for discoid lateral meniscus (DLM), to assess whether the degeneration of the articular cartilage in the lateral compartment of the knee progressed, and to evaluate clinical results.

Methods: Among the patients who underwent arthroscopic partial meniscectomy for DLM between January 1997 and December 2011, those who were aged 40 or below at surgery were followed up for at least 3 years, and received at least 2 follow-up MRIs that were retrospectively reviewed. MRIs were done in symptomatic knees.

Does Lateral Meniscal Allograft Transplantation Using the Keyhole Technique Restore the Anatomic Location of the Native Lateral Meniscus?

Background: It is important to restore the normal anatomy of the native meniscus in meniscal allograft transplantation (MAT) for successful surgical results.

Purpose/hypothesis: The purpose of this study was to compare the anatomic positions of the anterior horn (AH) and posterior horn (PH) between the preoperative lateral meniscus and postoperative meniscal allograft after lateral MAT using the keyhole technique. We hypothesized that the keyhole technique could restore the preoperative anatomy of the native lateral meniscus.

Does Medial Meniscal Allograft Transplantation With the Bone-Plug Technique Restore the Anatomic Location of the Native Medial Meniscus?

Background: Previous work has shown the importance of restoring the normal structure of the native meniscus with meniscal allograft transplantation.

Purpose/hypothesis: The purpose of this study was to compare the anatomic positions of the anterior horn and posterior horn between the preoperative medial meniscus and the postoperative meniscal allograft after medial meniscal allograft transplantation with the bone-plug technique. The hypothesis was that the bone-plug technique could restore the preoperative structure of the native medial meniscus.

Periprosthetic fractures following total knee arthroplasty.

Periprosthetic fractures after total knee arthroplasty may occur in any part of the femur, tibia and patella, and the most common pattern involves the supracondylar area of the distal femur. Supracondylar periprosthetic fractures frequently occur above a well-fixed prosthesis, and risk factors include anterior femoral cortical notching and use of the rotational constrained implant. Periprosthetic tibial fractures are frequently associated with loose components and malalignment or malposition of implants.

Complications after arthroscopic coracoclavicular reconstruction using a single adjustable-loop-length suspensory fixation device in acute acromioclavicular joint dislocation.

Purpose: The purpose of this study was to evaluate clinical and radiological outcomes after arthroscopically assisted coracoclavicular (CC) fixation using a single adjustable-loop-length suspensory fixation device for acute acromioclavicular dislocation and to report intraoperative and postoperative complications.

Methods: Eighteen consecutive patients with acute acromioclavicular dislocation underwent arthroscopically assisted CC fixation using a single TightRope (Arthrex, Naples, FL). Using the Rockwood classification, 3 patients had grade III dislocations, one patient had a grade IV dislocation, and 14 patients had grade V dislocations.

Outcome of Surgical Treatment of AO Type C Pelvic Ring Injury.

Purpose: To evaluate the radiologic and clinical outcomes of AO type C pelvic ring injury and identify the prognostic factors.

Materials And Methods: We studied 53 patients who were treated for AO type C pelvic ring injury from January 2002 to February 2010. Mean age and mean follow-up duration were 42.

Relationship between Tibial Bone Defect and Extent of Medial Release in Total Knee Arthroplasty.

Purpose: To understand the relationship between tibial bone defect and extent of medial release in total knee arthroplasty.

Materials And Methods: We evaluated 32 knees in 22 patients with variable degrees of tibial bone defect on medial plateau has undergone total knee arthroplasty. In this study, 31 cases had been diagnosed as degenerative osteoarthritis and 1 case was osteonecrosis.

A Comparison of the Clinical and Radiographic Results of Press Fit Condylar Rotating-Platform High-Flexion and Low Contact Stress Mobile Bearing Prosthesis in Total Knee Arthroplasty: Short term Results.

Purpose: This study compared the results of rotating-platform high-flexion (RP-F) total knee arthroplasty with low contact stress (LCS) for clinical and radiographical assessment after a short-term period.

Materials And Methods: 68 total knee arthroplasties using a RP-F and LCS system were analyzed retrospectively. Thirty-five of the 68 were osteoarthritic knees and were followed-up for more than 2 years.

Surgical treatment of habitual patella dislocation with genu valgum.

Habitual dislocation of patella is a rare disorder. Sometimes it is associated with angular deformity such as genu valgum. We experienced habitual patella dislocation associated with genu valgum that was treated with corrective osteotomy of distal femur and soft tissue realignment procedure including lateral release and medial reefing.

Comparison between Single and Dual Femoral Fixation for Anterior Cruciate Ligament Reconstruction with a Hamstring Autograft.

Purpose: The purpose of this study was to evaluate dual fixation with different fixation mechanisms, determine the advantages, and compare the outcomes between single and dual femoral fixation.

Materials And Methods: From April 2004 to September 2007, 19 patients who received single femoral fixation and 22 patients who received dual femoral fixation were enrolled in the study. Single femoral fixation was performed using a cross-pin expansion mechanism.

Curettage and calcium phosphate bone cement injection for the treatment of enchondroma of the finger.

Ten consecutive patients with digital enchondroma were treated by curettage and calcium phosphate bone cement (CPC) injection under digital nerve block. Mean patient age at surgery was 39 years old (range, 26-54), and the mean follow-up period was 19 months (range, 12-31). Two patients had a pathologic fracture at the first visit.