Human Regulatory T Cells: Understanding the Role of Tregs in Select Autoimmune Skin Diseases and Post-Transplant Nonmelanoma Skin Cancers.

Regulatory T cells (Tregs) play an important role in maintaining immune tolerance and homeostasis by modulating how the immune system is activated. Several studies have documented the critical role of Tregs in suppressing the functions of effector T cells and antigen-presenting cells. Under certain conditions, Tregs can lose their suppressive capability, leading to a compromised immune system.

A protocol to detect human CD4 T cell extracellular traps using scanning electron microscopy.

We present a protocol to detect extracellular traps (ETs) induced by Cutibacterium acnes in cultured T17 clones. We first describe the isolation of C. acnes-specific T17 clones by sterile cell sorting.