Publications by authors named "Nam N Hoai"

This review evaluates the effectiveness of veno-pulmonary support with an oxygenator using extracorporeal membrane oxygenation as a bridge to lung transplantation strategy in patients undergoing veno-venous extracorporeal membrane oxygenation while awaiting lung transplantation. Examining indications, contraindications, and clinical outcomes, the study highlights potential benefits, drawing insights from successful cases in South Korea and the United States. Despite limited sample sizes, veno-pulmonary support with an oxygenator using extracorporeal membrane oxygenation emerges as a promising approach for further investigation in lung transplantation support.

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This work successfully synthesized the Cnts/calcined Zn-Co-LDHs (Cnts@ZnC) hybrid material using the Zn-Co-LDHs precursor. Using the co-precipitation method, we synthesized Zn-Co-LDHs onto Cnts ranging in mass from 0 to 80 mg. These were subsequently calcined at 550 °C to yield Cnts@ZnC ( = 2, 4, 6, 8).

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Article Synopsis
  • This study investigates the effects of second litter syndrome (SLS) on the reproductive performance of sows, especially focusing on metrics like piglets born alive (PBA) and farrowing intervals (FI) across up to five reproductive cycles.
  • About 47.8% of sows experienced SLS, which significantly decreased their accumulative number of piglets born alive for the first two parities but showed comparable performance in later parities compared to sows without SLS.
  • The study concludes that SLS does not significantly harm future reproductive performance, suggesting that sows affected by SLS may not need to be culled, and calls for further research on the underlying mechanisms of PBA fluctuations.
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Background And Purpose: The acute vertebrobasilar occlusion associated with the poor prognosis, particularly tandem occlusion. However, few data on the efficacy of the endovascular therapy was indicated in this occlusion. We investigated whether the additional rescue extracranial vertebral stenting improved clinical outcome by modified Rankin scale (mRS) score within 3 months after the procedure.

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Background: Surgical reconstruction is often necessary for severe tracheobronchial stenosis resulting from tuberculosis (TB). However, the long-term efficacy of this approach remains unclear. This study investigated the safety and long-term outcomes of surgery for severe post-TB tracheobronchial stenosis.

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Article Synopsis
  • Probiotics, specifically QST 713, were examined for their impact on reproductive performance in multiparous sows during late gestation.
  • The study involved 115 sows divided into control and probiotic groups, assessing various reproductive parameters like birth weight and stillbirth rates.
  • Results showed that QST 713 reduced stillbirth and born dead rates while increasing piglet birth weight, indicating improved reproductive performance in sows.
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Background: This study aims to present the early and mid-term outcomes of combining minimally invasive mitral valve surgery (MIMVS) with tricuspid valve repair (TVR) at the authors' centre.

Methods: From January 2017 to March 2022, our centre treated a total of 67 patients with both MIMVS and TVR. Among these patients, 41 were women (61.

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Background And Aim: Among serotypes, serotype 2 is the most significant serotype that causes serious diseases in pigs and humans worldwide. The present study aimed to estimate the global prevalence of serotype 2 isolated from pigs, determine its trend, and explore the factors associated with this serotype.

Materials And Methods: We retrieved relevant published studies from PubMed, Scopus, and the Web of Science.

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Two new glycosides, sindosides A-B (1-2), along with 11 previously identified metabolites (3-13), were isolated from an ethanolic extract of the leaves of Sindora siamensis var. maritima. The structures of the purified phytochemicals were elucidated by interpreting their spectroscopic data (IR, NMR, and HRMS).

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Coronary artery bypass graft (CABG) surgery remains a pivotal cornerstone, offering established symptomatic alleviation and prognostic advantages for patients grappling with complex multivessel and left main coronary artery diseases. Despite the lucid guidance laid out by contemporary guidelines regarding the choice between CABG and percutaneous coronary intervention (PCI), a notable hesitation persists among certain patients, characterized by psychological reservations, knowledge gaps, or individual beliefs that sway their inclination toward surgical intervention. This comprehensive review critically synthesizes the prevailing guidelines, modern practices, and outcomes pertaining to CABG surgery, delving into an array of techniques and advancements poised to enhance both short-term and enduring surgical outcomes.

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Introduction: Pulmonary artery thrombosis presents a rare and formidable challenge, especially in individuals with untreated complex congenital heart diseases and concurrent valvular abnormalities.

Presentation Of Case: This case details a distinctive instance of pulmonary artery thrombosis in a patient with untreated congenital atrial septal defect, severe pulmonary hypertension, pulmonary aneurysm, valvular heart disease, and triple-positive antiphospholipid antibodies. Collaborative decision-making by a heart team guided the diagnostic and therapeutic processes, resulting in surgical interventions encompassing pulmonary thrombectomy, mitral and tricuspid regurgitation repair, and atrial septal defect closure.

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Six new acylated flavonoid glycosides namely barringosides J - O (1-6) along with tephrokaempferoside and barringoside D were isolated from the branches and leaves of Barringtonia pendula. The structural elucidation was confirmed by extensive analysis of their spectroscopic data including HRQTOFMS, 1D and 2D NMR experiments. Moderate inhibitory effects on LPS-induced NO production in RAW264.

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Chemical investigation of corn silk resulted in the isolation of nine secondary metabolites, including a new -kaurane diterpenoid, zeamaysditerpene A () and eight known compounds, stigmaydene A (), stigmaydene J (), stigmaydene L (), stigmane D (), demethyltorosaflavone D (), chrysoeriol 6---boivinopyranosyl-7---D-glucopyranoside (), deoxypodophyllotoxin (), and -peltatin glucoside (). Their structures were elucidated using a combination of spectroscopic methods, including 1D and 2D NMR and HRESIQTOF mass spectra. The absolute configuration of was deduced by applying electronic circular dichroism (ECD) calculation method.

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Five asterosaponins (-), including one new compound named protonodososide (), were isolated from the methanol extract of the starfish , after subjecting to various chromatographic separations. The structural elucidation was confirmed by careful analysis of the 1D, 2D NMR, and HR ESI QTOF mass spectra. The cytotoxicity of isolated compounds was evaluated on five human cancer cell lines including HepG2, KB, MCF7, LNCaP, and SK-Mel2.

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From the MeOH residue of branches and leaves, one new isoryanodane diterpene, barringisol (), and two new isoryanodane diterpene glucosides, barringisosides A and B ( and ), were obtained using various chromatographic isolations. The structural characterization was confirmed by spectroscopic methods including 1D, 2D NMR and HR-ESI-QTOF-MS. This is the first isolation of isoryanodane diterpene derivatives from species.

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Background And Aim: Previous findings regarding the effects of farrowing induction on the farrowing characteristics of sows are controversial. This study aimed to investigate the effects of farrowing induction on the following characteristics: (1) Proportion of sows that farrowed during working hours, (2) stillbirth rate, (3) number of stillbirths per farrow, (4) dystocia rate per farrow, (5) dystocia rate (the proportion of farrowings that had at least one dystocia event), (6) number of dystocia events per farrow, (6) farrowing duration, (7) birth interval, and (8) birth weight.

Materials And Methods: Thirty-eight Landrace x Yorkshire sows were randomly allocated into two groups; the control group and the treatment group.

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Recent studies have shown that probiotic supplementation during late gestation exerts some beneficial effects on reproductive performance of the sows. This study aimed to investigate effects of QST 713 supplementation in gilts on different reproductive criteria. A total of 94 Camborough-48 gilts at day 85 of gestation were randomly allocated into 2 groups: (1) control diet; (2) control diet + 4 × 10 CFU QST 713 per day.

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Limitations of live oocyst anticoccidial vaccines in poultry have led to a search for the new generation of anticoccidial vaccines. Several sources may influence the protective efficacy of the new generation of anticoccidial vaccine candidates. Therefore, the objective of this study was to explore the sources influencing the protective efficacy (in terms of the lesion score and the oocyst output) of the new-generation anticoccidial vaccine candidates from the challenge trials in chickens, using meta-analysis techniques.

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Article Synopsis
  • Researchers discovered three new sulfated naphthopyrone derivatives (delicapyrons F-H) and two new sulfated anthraquinone derivatives (delicaquinons A and B) from the Vietnamese crinoid Comanthus delicata.
  • The chemical structures of these compounds were determined using advanced techniques, including 1D and 2D-NMR and high-resolution mass spectrometry.
  • Among these compounds, 6 showed strong cytotoxic effects against prostate cancer cells, while the other compounds exhibited varying levels of cytotoxicity against melanoma and prostate cancer cell lines.
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Objective: The information about risk factors for a high stillbirth rate in piglets is inadequate. Therefore, this study was conducted to determine important risk factors for an extremely high stillbirth rate in a commercial pig farm in Vietnam.

Materials And Methods: This study included 628 piglets and 45 Landrace × Yorkshire sows.

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Three new chromanes, malloapeltas J-L (-), and one new flavone -glycoside, malloflavoside (), together with four known compounds, apigenin 6---D-xylopyranosyl-8---L-arabinopyranoside (), apigenin 6---D-glucopyranosyl-8---L-arabinopyranoside (), apigenin 7---D-apiofuranosyl-(1→2)--D-glucopyranoside (), and acantrifoside E () were isolated from the methanol extract of the leaves of . Their chemical structures were determined using spectroscopic methods, including 1D, 2D NMR, and HR-ESI-MS methods. All the isolated compounds were evaluated their cytotoxic activity against human prostate cancer (PC-3) and human breast cancer (MCF-7) cells, but none of them showed cytotoxicities on both human cancer cell lines.

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Few studies have investigated risk factors for dystocia in swine, although this birthing abnormality can compromise welfare of both sows and piglets by increasing stillbirth rate and decreasing sow productivity. This study aimed to determine risk factors associated with dystocia at piglet level in cloprostenol-induced farrowings. A dystocia event was recorded when a birth interval exceeded 45  or when manual extraction was applied.

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Penicillium is a rich source of bioactive compounds. Among all Penicillium species, Penicillium oxalicum has been reported to produce various types of secondary metabolites, including alkaloids, phenolics, and tetrahydroxanthone dimeric compounds, exhibiting many pharmacological effects, such as antiviral, antibacterial, and cytotoxic activities. Three secondary metabolites were isolated from a fermented culture of the sponge-associated fungal strain P.

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One new phenylpropanoid glycoside, myxosmoside I () and six known compounds, arenarioside (), verbacoside (), 3-formylindole (), 5-hydroxymethyl furfural (), D-manitol (), and glycerol monooleate () were isolated from the roots of Wall Blume. Their chemical structures were determined by 1D-, 2D-NMR, and mass spectra, chemical methods, and compared with those reported in the literature. All compounds were evaluated for -glucosidase inhibitory effect.

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Aplydactylonins A-C (1-3), three new sesquiterpenes, were isolated from the Vietnamese sea hare Aplysia dactylomela. Their structures and absolute configurations were elucidated based on spectroscopic analysis, X-ray crystallography, and density functional theory (DFT) calculations of NMR and ECD data. Compound 2 exhibited cytotoxicity against HepG2, DU145 and A549 cells with respective IC values of 4.

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