Efficient 3D FISP-MRF at 0.55 T using long spiral readouts and concomitant field effect mitigation.

Purpose: To demonstrate the feasibility of SNR-efficient 3D fast imaging with steady state precession MR fingerprinting (FISP-MRF) using long spiral readouts with mitigation of concomitant field effects at 0.55 T.

Methods: Fourteen FISP-MRF sequences with different spiral readout lengths (2.

3D deuterium metabolic imaging (DMI) of the human liver at 7 T using low-rank and subspace model-based reconstruction.

Purpose: To implement a low-rank and subspace model-based reconstruction for 3D deuterium metabolic imaging (DMI) and compare its performance against Fourier transform-based (FFT) reconstruction in terms of spectral fitting reliability.

Methods: Both reconstruction methods were applied on simulated and experimental DMI data. Numerical simulations were performed to evaluate the effect of increasing acceleration factors.

Single breath-hold volumetric lung imaging at 0.55T using stack-of-spiral (SoS) out-in balanced SSFP.

Purpose: To develop a robust single breath-hold approach for volumetric lung imaging at 0.55T.

Method: A balanced-SSFP (bSSFP) pulse sequence with 3D stack-of-spiral (SoS) out-in trajectory for volumetric lung imaging at 0.

Multidimensional RF pulse design with consideration of concomitant field effects.

Purpose: To develop a small-tip multidimensional RF pulse design procedure that incorporates linear time-invariant gradient imperfections and concomitant field effects. This could be particularly important for contemporary low-field MRI systems with high-performance gradients.

Theory And Methods: We developed an extension of the small-tip excitation k-space formalism, where concomitant fields were approximated as a Bloch-Siegert shift in the rotating frame.

Improved abdominal T1 weighted imaging at 0.55T.

Purpose: Breath-held fat-suppressed volumetric T1-weighted MRI is an important and widely-used technique for evaluating the abdomen. Both fat-saturation and Dixon-based fat-suppression methods are used at conventional field strengths; however, both have challenges at lower field strengths (<1.5T) due to insufficient fat suppression and/or inadequate resolution.

Repeat it without me: Crowdsourcing the T mapping common ground via the ISMRM reproducibility challenge.

Purpose: T mapping is a widely used quantitative MRI technique, but its tissue-specific values remain inconsistent across protocols, sites, and vendors. The ISMRM Reproducible Research and Quantitative MR study groups jointly launched a challenge to assess the reproducibility of a well-established inversion-recovery T mapping technique, using acquisition details from a seminal T mapping paper on a standardized phantom and in human brains.

Methods: The challenge used the acquisition protocol from Barral et al.

Replication of the bSTAR sequence and open-source implementation.

Purpose: The reproducibility of scientific reports is crucial to advancing human knowledge. This paper is a summary of our experience in replicating a balanced SSFP half-radial dual-echo imaging technique (bSTAR) using open-source frameworks as a response to the 2023 ISMRM "repeat it with me" Challenge.

Methods: We replicated the bSTAR technique for thoracic imaging at 0.

Submillimeter lung MRI at 0.55 T using balanced steady-state free precession with half-radial dual-echo readout (bSTAR).

Purpose: To demonstrate the feasibility of high-resolution morphologic lung MRI at 0.55 T using a free-breathing balanced steady-state free precession half-radial dual-echo imaging technique (bSTAR).

Methods: Self-gated free-breathing bSTAR (TE /TE /TR of 0.

Lung parenchyma transverse relaxation rates at 0.55 T.

Purpose: To determine R and transverse relaxation rates in healthy lung parenchyma at 0.55 T. This is important in that it informs the design and optimization of new imaging methods for 0.

Contrast-optimal simultaneous multi-slice bSSFP cine cardiac imaging at 0.55 T.

Purpose: To determine if contemporary 0.55 T MRI supports the use of contrast-optimal flip angles (FA) for simultaneous multi-slice (SMS) balanced SSFP (bSSFP) cardiac function assessment, which is impractical at conventional field strengths because of excessive SAR and/or banding artifacts.

Methods: Blipped-CAIPI bSSFP was combined with spiral sampling for ventricular function assessment at 0.

MaxGIRF: Image reconstruction incorporating concomitant field and gradient impulse response function effects.

Purpose: To develop and evaluate an improved strategy for compensating concomitant field effects in non-Cartesian MRI at the time of image reconstruction.

Theory: We present a higher-order reconstruction method, denoted as MaxGIRF, for non-Cartesian imaging that simultaneously corrects off-resonance, concomitant fields, and trajectory errors without requiring specialized hardware. Gradient impulse response functions are used to predict actual gradient waveforms, which are in turn used to estimate the spatiotemporally varying concomitant fields based on analytic expressions.

Relationship Between Balance, Gait, and Activities of Daily Living in Older Adults With Dementia.

Introduction: Gait characteristics are closely associated with executive functions including basic and high-level cognitive processes such as attention, working memory, decision-making, and problem-solving. Impaired cognitive function resulting from dementia is associated with loss of balance and poor activities of daily living (ADLs). If associations between gait parameters, balance, and ADLs are observed, then quantitative gait analysis may be optimal for reinforcing balance and ADL assessments in people with dementia.

Numerical approximation to the general kinetic model for ASL quantification.

Purpose: To develop a numerical approximation to the general kinetic model for arterial spin labeling (ASL) quantification that will enable greater flexibility in ASL acquisition methods.

Theory: The Bloch-McConnell equations are extended to include the effects of single-compartment inflow and outflow on both the transverse and longitudinal magnetization. These can be solved using an extension of Jaynes' matrix formalism with piecewise constant approximation of incoming labeled arterial flow and a clearance operator for outgoing venous flow.

MR spectroscopy using static higher order shimming with dynamic linear terms (HOS-DLT) for improved water suppression, interleaved MRS-fMRI, and navigator-based motion correction at 7T.

Purpose: To interleave global and local higher order shimming for single voxel MRS. Single voxel MR spectroscopy requires optimization of the B field homogeneity in the region of the voxel to obtain a narrow linewidth and provide high data quality. However, the optimization of local higher order fields on a localized MRS voxel typically leads to large field offsets outside that volume.

Improved real-time tagged MRI using REALTAG.

Objectives: To evaluate a novel method for real-time tagged MRI with increased tag persistence using phase sensitive tagging (REALTAG), demonstrated for speech imaging.

Methods: Tagging is applied as a brief interruption to a continuous real-time spiral acquisition. REALTAG is implemented using a total tagging flip angle of 180° and a novel frame-by-frame phase sensitive reconstruction to remove smooth background phase while preserving the sign of the tag lines.

Best Core Stabilization for Anticipatory Postural Adjustment and Falls in Hemiparetic Stroke.

Objectives: To compare the effects of conventional core stabilization and dynamic neuromuscular stabilization (DNS) on anticipatory postural adjustment (APA) time, balance performance, and fear of falls in chronic hemiparetic stroke.

Design: Two-group randomized controlled trial with pretest-posttest design.

Setting: Hospital rehabilitation center.

Unipedal postural stability in nonathletes with core instability after intensive abdominal drawing-in maneuver.

Context: The exact neuromechanical nature and relative contribution of the abdominal drawing-in maneuver (ADIM) to postural instability warrants further investigation in uninjured and injured populations.

Objective: To determine the effects of the ADIM on static core and unipedal postural stability in nonathletes with core instability.

Design: Controlled laboratory study.

A novel spinal kinematic analysis using X-ray imaging and vicon motion analysis: a case study.

This study highlights a novel spinal kinematic analysis method and the feasibility of X-ray imaging measurements to accurately assess thoracic spine motion. The advanced X-ray Nash-Moe method and analysis were used to compute the segmental range of motion in thoracic vertebra pedicles in vivo. This Nash-Moe X-ray imaging method was compared with a standardized method using the Vicon 3-dimensional motion capture system.

Effects of functional movement strength training on strength, muscle size, kinematics, and motor function in cerebral palsy: a 3-month follow-up.

We investigated the long-term effects of comprehensive hand repetitive intensive strengthening training (CHRIST) on strength, morphological muscle size, kinematics, and associated motor functional changes in children with cerebral palsy (CP). Ten children (5 boys, 5 girls; age range, 6-11 years, mean age, 8.6 years) participated in the study.

Comparative neuroimaging in children with cerebral palsy using fMRI and a novel EEG-based brain mapping during a motor task--a preliminary investigation.

Purpose: The purpose of this study was to compare topographical maps using a novel EEG-based brain mapping system with fMRI in normal and children with cerebral palsy (CP) during a grasping motor task.

Method: A normal child (mean ± SD = 13 ± 0 yrs) and four children with CP (mean ± SD = 10.25 ± 2.

Effects of the progressive walking-to-running technique on gait kinematics, ultrasound imaging, and motor function in spastic diplegic cerebral palsy - an experimenter-blind case study.

Purpose: The purpose of this study was to investigate the effects of the progressive walking-to-running technique (PWRT) in a child with spastic diplegic cerebral palsy (CP).

Design: A single case study with pre-/post-test.

Subject: An 11-year-old male, diagnosed with spastic diplegic CP.

Rapamycin inhibits both motility through down-regulation of p-STAT3 (S727) by disrupting the mTORC2 assembly and peritoneal dissemination in sarcomatoid cholangiocarcinoma.

Cholangiocarcinoma (CC) is a malignant epithelium neoplasm that originates from the bile epithelium and for which there are few therapeutic strategies. The mTOR pathway involved in many cellular processes was reported to be up-regulated in various cancers. We investigated the activation of the AKT/mTOR pathway in CC cell lines with different degrees of dedifferentiation and found that rapamycin could suppress the motility and the peritoneal dissemination of sarcomatoid SCK cells.

Feasibility and test-retest reliability of an electroencephalography-based brain mapping system in children with cerebral palsy: a preliminary investigation.

Objective: To investigate the feasibility and test-retest reliability of a novel electroencephalography (EEG)-based brain mapping system in healthy children and children with cerebral palsy (CP).

Design: Correlation statistics.

Setting: University brain mapping and neurorehabilitation laboratory.

The effect of robo-horseback riding therapy on spinal alignment and associated muscle size in MRI for a child with neuromuscular scoliosis: an experimenter-blind study.

Purpose: This case study was conducted to highlight the clinical and radiological features of a patient with progressive neuromuscular scoliosis before and after robo-horseback riding therapy (HBRT).

Design: A clinical, laboratory, and radiological analysis of a single case.

Subject: An 11-year-old child, dignosed right thoracolumbar neuromuscular scoliosis secondary to cerebral palsy.

Near-infrared fluorescence imaging using a protease-specific probe for the detection of colon tumors.

Background/aims: Early tumor detection is crucial for the prevention of colon cancer. Near-infrared fluorescence (NIRF) imaging using a target-activatable probe may permit earlier disease detection. Matrix metalloproteinases (MMPs) participate in tumorigenesis and tumor growth.