Publications by authors named "Nakyung Oh"
The CUT&RUN technique facilitates detection of protein-DNA interactions across the genome. Typical applications of CUT&RUN include profiling changes in histone tail modifications or mapping transcription factor chromatin occupancy. Widespread adoption of CUT&RUN is driven, in part, by technical advantages over conventional ChIP-seq that include lower cell input requirements, lower sequencing depth requirements, and increased sensitivity with reduced background signal due to a lack of cross-linking agents that otherwise mask antibody epitopes.
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- Subsets of LINE-1 retrotransposons can move around within the human genome, which may negatively impact the fitness of host cells and is linked to certain cancers.
- Researchers Thawani et al. and Baldwin et al. published papers revealing the structure of LINE-1 ORF2p, a key protein involved in this process, shedding light on how retrotransposition works.
- Understanding the mechanisms of LINE-1 ORF2p is essential for developing targeted drugs to inhibit its reverse transcriptase function and minimize its harmful effects.
Adults with short stature have been previously reported to have increased risk of cardiovascular events and hyper-LDL-cholesterolemia. We aimed to assess the association between height and lipid profiles among Korean adolescents and adults. We analyzed data from the Korea National Health and Nutrition Examination Survey from 2007 to 2015, from 37,889 individuals (aged 12-59 years).
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