Immunoglobulins in newborns, particularly in term SFD infants.

The following results were obtained by analyzing serum IgG, IgM and IgA of blood from the umbilical cord chiefly of small-for-date infants (term SFD infants): (1) The serum IgG level was higher in the infant's blood than in the mother's blood in the cases of appropriate-for-date infants (term AFD infants). Its fetus/ mother ratio was 1.25 +/- 0.

Immunochemical quantitation of serum complement components in SFD and AFD infants.

Components of complement (protein concentrations of C1q, C3, C3-activator, C4, C5 and C9 and whole complement (hemolytic activity)) were measured in sera from full-term small-for-date (SFD) and appropriate-for-date (AFD) infants and their mothers. (1) Half the SFD infants showed lower C1q levels than the AFD infants. (2) SFD infants showed the same levels of C3 as AFD infants.

Prophylactic photocoagulation of the fellow eye in exudative senile maculopathy. A preliminary report.

Information on the fate of the fellow eye in patients who have suffered loss of central vision in the first eye due to exudative senile maculopathy suggests that there is a high incidence of later loss of vision in the second eye due to the same disease process. It has been speculated that prophylactic photocoagulation of the macula in the fellow eye might have a protective effect. This is a preliminary report of a series of patients in which argon laser photocoagulation of the second eye has been performed.

Subacute sclerosing panencephalitis.

A 17-year-old white woman had an acute left maculopathy of unknown etiology. She was in excellent health and had only had rubeola at 3 years of age. Hruby lens examination of the left eye, visual acuity of 6/60 (20/200), revealed a normal vitreous, macular edema, intraretinal hemorrhage, and cotton-wool exudates.

Left ventricular asynergy in mitral valve diseases. A cineangiographic study.

Mode of left ventricular contraction was studied by cine left ventriculography in 22 cases with mitral valve diseases and 7 control cases. In rheumatic mitral valve diseases, local hypokinesis of the left ventricular wall and poor contraction of the mitral annulus were observed frequently, at various location and to various extent. Transient asynergic motion of local wall was also seen either during systole or during diastole.

Hemodynamic and clinical significances of atrial fibrillation, pulmonary vascular resistance and left ventricular function in rheumatic mitral stenosis.

Seventy-four patients with rheumatic mitral stenosis were catheterized and hemodynamic and clinical significances of atrial fibrillation, pulmonary vascular resistance and left ventricular function were studied. These data were also compared to those in the 6 control cases. In addition to the correlation of mitral valve area to the functional classification of patients, significance of atrial fibrillation was also demonstrated.

Studies on pharmacological and biochemical properties of deamino-dicarba-[GLY-7]-oxytocin (Y-5350).

Pharmacological and biochemical properties were investigated on deamino-dicarba-[Gly-7]-oxytocin (Y-5350). This is a newly developed compound, in which the disulfide bond and [Pro-7] of deamino-oxytocin are substituted by an ethylene linkage and glycine respectively. Bioassayed Y-5350 exhibited 202.