Publications by authors named "Najmul Hassan Shah"

Article Synopsis
  • - New guidelines suggest a 5-year survival rate of at least 60% for hepatocellular carcinoma (HCC) patients receiving living donor liver transplants, and this study looks at outcomes for those who meet expanded criteria.
  • - The study included 208 patients, reporting 5-year and 10-year survival rates of 67% and 61% respectively, with a recurrence risk of about 20.5% at 5 years and 22.5% at 10 years; larger tumors and higher AFP levels correlated with increased recurrence risk.
  • - Patients classified as low-risk for HCC based on tumor size and AFP levels had a 5-year recurrence risk similar to those meeting the traditional Milan criteria,
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Background: As a quality assessment tool, failure to rescue (FTR) has been employed in various surgical specialties. However, its role in liver transplantation has only recently been explored. To the best of our knowledge, role of FTR in living donor liver transplant (LDLT) has not been assessed previously.

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Biliary complications are the most common post-liver transplant (LT) complications with an incidence of 15%-45%. Furthermore, such complications are reported more frequently in patients who undergo a living-donor LT compared to a deceased-donor LT. Most post-LT biliary complications involve biliary strictures, bile leakage, and biliary stones, although many rarer events, such as hemobilia and foreign bodies, contribute to a long list of related conditions.

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BACKGROUND The Barcelona clinic liver cancer (BCLC) staging system is considered the standard of care for hepatocellular carcinoma (HCC) management. It has various limitations, including lack of second-line treatment options and combination therapy. We prospectively collected data on our HCC patients based on a new decision-making tool (NDT).

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Background. Concomitant vascular injury might adversely impact outcomes after iatrogenic bile duct injury (IBDI). Whether a new HPB center should embark upon repair of complex biliary injuries with associated vascular injuries during learning curve is unknown.

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Objective: To determine the outcomes of paediatric living donor liver transplantation (LDLT) recipients from Pakistan in terms of 90-day morbidity and mortality.

Study Design: Cohort study.

Place And Duration Of Study: Shifa International Hospital, Islamabad, Pakistan, between April 2012 and April 2015.

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Background: Metastatic para aortic lymph nodes (PALN) in patients with peri ampullary cancer entail poor prognosis. Role of curative surgery in these patients remains debatable. The objective of the current study was to evaluate outcome after extended pancreaticoduodenectomy (PD) in patients with and without positive PALN.

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Objective: To determine the outcome of living-donor liver transplant (LDLT) donors from the first liver transplant program in Pakistan.

Study Design: Cohort study.

Place And Duration Of Study: Shifa International Hospital, Islamabad, from April 2012 to August 2014.

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Hepatocellular carcinoma (HCC) ranks second amongst all causes of cancer deaths globally. It is on a rise in Pakistan and might represent the most common cancer in adult males. Pakistan contributes significantly to global burden of hepatitis C, which is a known risk factor for HCC, and has one of the highest prevalence rates (>3%) in the world.

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Introduction: Safety of extended lymphadenectomy (EL) ± vascular resection in patients undergoing pancreaticoduodenectomy (PD) in resource limited settings is not well established. The objective of this study was to report outcomes of PD resection with EL ± vascular resection from Pakistan and review national literature.

Methods: Data of patients who underwent PD between 2011 and 2014 was reviewed.

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Background: Living donor liver transplantation (LDLT) involves healthy individuals undergoing voluntary major hepatic resection. LDLT program only started in 2012 in Pakistan and its impact on donor's quality of life (QOL) post resection is not known. The objective of this study was to determine health-related QOL in donors who underwent hepatectomy in country's first liver transplant program.

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Living donor liver transplantation (LDLT) is the only treatment option for patients with end-stage liver disease (ESLD) where cadaveric donors are not available. In developing countries, the inception of LDLT programs remains a challenge. The first successful liver transplantation program in Pakistan started transplantation in 2012.

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