The deficiency of Surfactant Protein B (SPB) in Amniotic Fluid (AF) has been associated with severe respiratory pathologies in newborns such as respiratory distress syndrome (RDS). Early-stage diagnosis of these respiratory complications by monitoring the SPB in AF could be a significant clinical tool and the first step toward adopting efficient therapy. In this work, we report the development of a novel sensitive electrochemical immunosensor for the detection of SPB in human AF samples.
View Article and Find Full Text PDFInfectious diseases caused by Aeromonas salmonicida (A. salmonicida) have a huge impact and produce significant losses in aquaculture and fish farming. Fish pathogen early detection is a critical step for the rapid identification and prevention of these problems.
View Article and Find Full Text PDFA novel and simple biosensor for the determination of bisphenol A (BPA) based on xanthine oxidase (XOD) enzymatic inhibition has been developed. The biosensor was prepared from xanthine oxidase immobilised by crosslinking with glutaraldehyde, with hypoxanthine as enzyme substrate, and was successfully applied to the determination of BPA using fixed potential amperometry. Biosensor performance was optimised with respect to the applied potential, influence of pH of the electrolyte solution, XOD loading and the substrate concentration.
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