Effect of the Hydoxyurea in Yemeni Transfusion-Dependent β-Thalassemia Patients.

The response to hydroxyurea (HU) therapy of 44 Yemeni transfusion-dependent β-thalassemia (β-thal) patients in Sana'a City, Yemen, was assessed. All patients were treated with a dose of 15 mg/kg/day HU for 4-10 months. Thirty-six patients responded partially to HU with clinical improvement of anemia and extramedullary hematopoiesis features, whereas the rest remained almost at the same baseline levels of transfusion dependency.

Pregnancy outcomes of mothers aged 17 years or less.

Objective: To study the obstetric complications of women who become pregnant at aged 17 years old or less.

Methods: A retrospective study was performed from January to December 2009 at Al-Thawra General Hospital, Sana'a, Yemen. We included all women aged 17 years or less who delivered in the hospital with singleton births after 24 weeks gestational age.