Anti-inflammatory activity of crude and detoxified leaves of Daphne oleoides Schreb. on carrageenan-induced paw edema in wistar rats.

Background: Mazaryun (Daphne oleoides Schreb.) is used as an anti-inflammatory drug in Unani medicine after detoxification, as it is defined under fourth-degree drugs.

Objective(s): To evaluate and compare the anti-inflammatory activity of crude and detoxified Mazaryun in maximum and minimum doses.

Scientific appraisal of Unani concept of islah-e-advia (rectification/purification of drugs) and its importance.

Ethnopharmacological Relevance: Unani system of medicine uses drugs from plants, minerals and animals (Mawaleed-e-salasa) origin. Most of the drugs used are believed to be safe, but some drugs may have toxins and produce harmful effects, so it is very important to remove the toxins or to minimize their harmful effects before using, so as to increase their therapeutic values and make easy for use.

Aim Of The Study: To explore the concept, aims and objectives of islah-e-advia (rectification/purification of drugs) in Unani system of medicine.