Investigation of the surface confinement effect of copper nanoclusters: construction of an ultrasensitive fluorescence turn-on bio-enzyme sensing platform.

Copper nanoclusters (CuNCs) have attracted considerable research interest due to their good physicochemical properties, ease of preparation, and low price. However, the low quantum yield and poor stability in aqueous solutions have greatly limited their applications. In order to improve the fluorescence properties and stability of CuNCs, in this paper, the surface confinement effect of CuNCs based on 2D layered double hydroxide (LDH) was proposed to prepare the fluorescent composites of glutathione protected CuNCs and LDH (GS-CuNCs/LDH) with excellent quantum yield and long fluorescence lifetime.

A modulation approach for covalent organic frameworks: Application to solid phase microextraction of phthalate esters.

A modulation approach with 4-hydroxybenzhydrazide as the modulating agent was designed for constructing 2,4,6-triphenoxy-1,3,5-benzene-based covalent organic frameworks (COFs). The COFs materials were employed as solid phase microextraction (SPME) coatings for the extraction of phthalate esters (PAEs). Various experimental conditions including extraction temperature, extraction time, salt concentration, and desorption time were investigated and optimized.

Electrostatically controlled fluorometric assay for differently charged biotargets based on the use of silver/copper bimetallic nanoclusters modified with polyethyleneimine and graphene oxide.

An electrostatically controlled fluorometric assay is described that is based on the use of silver/copper bimetallic nanoclusters. The nanoclusters were coated with polyethyleneimine (PEI-Ag/CuNCs). At pH 7.

Cobalt Phthalocyanine Tetracarboxylic Acid Functionalized Polymer Monolith for Selective Enrichment of Glycopeptides and Glycans.

In this study, poly(glycidyl methacrylate-ethyleneglycol dimethacrylate) monolith functionalized with cobalt phthalocyanine tetracarboxylic acid is prepared. The polymer monolithic material is used for glycopeptides enrichment coupled with MALDI-TOF MS. By taking advantage of cobalt phthalocyanine including hydrogen bonds between isoindole subunits of phthalocyanine and glycans, coordination interaction between cobalt and glycopeptides, the monolithic material is successfully applied to the enrichment of glycopeptides efficiently and selectively.

[Preparation of cobalt phthalocyanine functionalized polymer monolith and application to enrichment of transferrin glycopeptides].

Poly(glycidyl methacrylate-ethyleneglycol dimethacrylate) (Poly(GMA-EDMA)) monolith functionalized with cobalt phthalocyanine tetracarboxylic acid (CoPcTc) was prepared. The monolith was used for transferrin (Tf) glycopeptide enrichment. By taking advantage of hydrogen bonds between isoindole subunits of phthalocyanine and glycans and coordination interaction between cobalt and glycopeptides, the monolithic material was efficient and selective.

Preparation of carboxylatocalix[4]arene functionalized magnetic polyionic liquid hybrid material for the pre-concentration of phthalate esters.

In this work, we designed a novel hybrid material based on the polymerization of an ionic liquid on a magnetic core and further functionalized with carboxylatocalix[4]arene. Scanning electron microscope, transmission electron microscope, Fourier transform infrared spectroscopy, thermal gravimetric-derivative thermogravimetric analysis, energy dispersive X-ray spectroscopy, X-ray diffractometer, and vibrating sample magnetometer were utilized to examine the physicochemical properties of the hybrid material obtained. The material was used as the adsorbent for magnetic solid-phase extraction of phthalate esters.

Anchoring β-cyclodextrin modified lysine to polymer monolith with biotin: specific capture of plasminogen.

Plasminogen (Plg) is a kind of glycoprotein which plays an important role in cell migration. The determination of Plg content can directly reflect the abnormal manifestation of fibrinolytic system dysfunctions. In the present work, lysine (Lys)-based adsorbents were prepared for the specific capture of Plg through the covalent binding of Lys with a polymer monolithic substrate.

Highly selective enrichment of phosphopeptides by on-chip indium oxide functionalized magnetic nanoparticles coupled with MALDI-TOF MS.

Selective and efficient preconcentration is indispensable for low concentration of phosphopeptides in phosphorylated protein-related samples prior to MS-based analysis. Herein, an on-chip system coupled magnetic SPE with MALDI-TOF MS was designed. A metal oxide affinity chromatography material, indium oxide, was coated on the surface of Fe O magnetic nanoparticles to prepare the adsorbent, spatially confined with an applied magnetic field.

[Synthesis of Magnetic Metal Organic Framework Fe3O4@NH2-MIL-53 (Al) Materials and Application to the Adsorption of Lead].

Metal organic framework, a novel class of organic inorganic hybrid functional materials, has been widely used in the fields of gas adsorption, catalysis, separation, and biological medicine due to its large specific surface area, diverse structural, and adjustable channel. In this work, a new amine-functionalized magnetic metal-organic framework material was synthesized. Nano-Fe3O4 was prepared by a solvothermal method, after which polyvinyl pyrrolidone was employed to modify Fe3O4.