Publications by authors named "Naito Kanon"
Article Synopsis
- Rising antimicrobial resistance (AMR) in Salmonella Typhi poses a significant threat to typhoid treatment, especially in high-burden countries like Bangladesh, where long-term data is lacking.
- The study analyzed typhoid cases in Dhaka from 1999 to 2022, finding a decrease in multidrug resistance (MDR) from 38% to 17% and a drop in cotrimoxazole consumption, while resistance to ciprofloxacin remained high (>90%).
- With a noted decline in MDR, the research suggests that first-line antibiotics may be safely reintroduced for treating typhoid fever, pending further decreases in resistance rates.
Purpose: Typhoid fever causes substantial morbidity and mortality in Bangladesh. The government of Bangladesh plans to introduce typhoid conjugate vaccines (TCV) in its expanded program on immunization (EPI) schedule. However, the optimal introduction strategy in addition to the costs and benefits of such a program are unclear.
View Article and Find Full Text PDFThe 10-valent pneumococcal conjugate vaccine (PCV10) was introduced in March 2015 in Bangladesh. In this study, we aimed to estimate the impact of PCV10 on invasive pneumococcal disease (IPD) identified by blood cultures and severe pneumonia identified clinically and its effectiveness on invasive disease caused by vaccine serotypes. We conducted population-based surveillance among children aged 2- <24 months between April 2012 through March 2019 in Mirzapur, a rural sub-district of Bangladesh.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the effects of SARS-CoV-2 on neonates in Bangladesh, revealing a significant number of infections among hospitalized babies, most of whom had non-SARS-CoV-2 related health issues.
- Out of 83 tested neonates, 26 were positive for the virus, with several developing serious health complications; follow-up showed a concerning mortality rate among those infected.
- The findings highlight the pressing need to improve understanding and treatment of COVID-19 in neonates within low- and middle-income countries, as existing healthcare challenges may worsen health outcomes.