Publications by authors named "Naira Josele Neves Brito"

The indiscriminate use of oral ferrous sulfate (FeSO) doses induces significant oxidative damage to health. However, carotene-rich foods such as buriti oil can help the endogenous antioxidant defense and still maintain other body functions. This study aimed to assess the effects of buriti oil intake in iron-overloaded rats by FeSO administration.

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Background: Zinc is an important cause of morbidity, particularly among young children. The dietary, functional, and biochemical indicators should be used to assess zinc status and to indicate the need for zinc interventions.

Objective: The purpose of this study was to determine the zinc status and reference intervals for serum zinc concentration considering dietary, functional, and biochemical indicators in apparently healthy children in the Northeast Region of Brazil.

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Background: Zinc is an essential nutrient that is required for numerous metabolic functions, and zinc deficiency results in growth retardation, cell-mediated immune dysfunction, and cognitive impairment.

Objective: This study evaluated nutritional assessment methods for zinc supplementation in prepubertal non-zinc-deficient children.

Design: We performed a randomised, controlled, triple-blind study.

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Background: The prevalence of abnormal nutritional status has increased in children and adolescents. Nutritional assessment is important for monitoring the health and nutritional status. Bioelectrical impedance vector analysis (BIVA) combines changes in tissue hydration and structure and body composition that can be assessed.

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Objective: Because most publications on growth and development deal with children with zinc deficiency, we decided to study the effects of this micronutrient on the secretion of growth hormone (GH), insulin-like growth factor 1 (IGF1), insulin-like growth factor binding protein 3 (IGFBP3), osteocalcin (OCN), and alkaline phosphatase (ALP) in healthy and eutrophic children. This study is original because the methodology was unique.

Methods: Forty schoolchildren participated in the study, 17 females and 23 males, aged 8 and 9 years.

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Article Synopsis
  • A study was conducted on 30 healthy children aged 8 to 9 years to analyze the effects of 3 months of oral zinc supplementation on their iron status.
  • The children were divided into a control group receiving a placebo and an experimental group receiving 10 mg of zinc daily, with blood samples taken at various intervals.
  • While zinc supplementation significantly increased serum zinc levels and improved overall nutrient intake, it was found to decrease serum iron levels without leading to anemia.
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Berardinelli-Seip syndrome (BSS) is a very rare disorder characterized by near-complete absence of adipose tissue from birth or early infancy, hypoleptinemia, hypertriglyceridemia, insulin resistance, diabetes mellitus, and other clinical signals. It is caused by mutations in AGPAT2 or Gng3lg. We evaluated 10 BSS patients and 10 healthy subjects.

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