Publications by authors named "Naina Vinay Mudugal"
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Synopsis of recent research by authors named "Naina Vinay Mudugal"
- Naina Vinay Mudugal's research primarily focuses on identifying and validating essential and vulnerable targets in bacteria, particularly in Mycobacterium tuberculosis and other pathogens, to aid in drug discovery efforts.
- Key findings include the establishment of conditional expression systems, the recognition of Mycobacterium tuberculosis topoisomerase I as a potential anti-tubercular target, and the vulnerability of MurC in peptidoglycan biosynthesis as a target for new antibacterials.
- Mudugal's work emphasizes the importance of understanding enzyme mechanisms, such as pantothenate kinase in Mycobacterium tuberculosis, leading to the discovery of diverse classes of inhibitors aimed at therapeutic development.
