Factors influencing metal concentrations in hair and nails during longitudinal follow-up of apprentice welders.

The aim of this study was to determine factors influencing observed increased metal biomarkers of exposure levels in a group of 116 Quebec apprentice welders during a longitudinal follow-up of exposure. Analysis of 14 metals was carried out in hair, fingernail, and toenail samples taken from participants over the course of their welding curriculum at 6 different times. Personal and socio-demographic characteristics, lifestyle habits, and other potential confounding factors were documented by questionnaire.

Follow-up Biomonitoring Study of Metal Exposure in Apprentice Welders in Montreal, Quebec, During Gas Metal Arc Welding (GMAW).

Welding activities are known to expose workers to metal fumes, but few studies have focused on assessing the internal exposure of apprentices in learning environments. This study aimed at determining internal doses of metals in apprentices performing gas metal arc welding (GMAW) during their training course. A total of 85 apprentice welders were assessed, and multi-elements were measured in urine, hair, fingernail, and toenail samples collected at the beginning of the program, and at the beginning and end of GMAW practical training.

Biomonitoring of exposure to multiple metal components in urine, hair and nails of apprentice welders performing shielded metal arc welding (SMAW).

Welding fumes are associated with various diseases. Increased air levels of metals were reported during welding. However, few multielement biomonitoring studies were conducted to assess the actual dose of metal components absorbed in apprentice welders in a learning environment.

Excretion time courses of lambda-cyhalothrin metabolites in the urine of strawberry farmworkers and effect of coexposure with captan.

There are limited literature data on the impact of coexposure on the toxicokinetics of pesticides in agricultural workers. Using the largely employed pyrethroid lambda-cyhalothrin (LCT) and fungicide captan as sentinel pesticides, we compared individual temporal profiles of biomarkers of exposure to LCT in strawberry field workers following an application episode of LCT alone or in coexposure with captan. Participants provided all urine voided over a 3-day period after an application of a pesticide formulation containing LCT alone (E1) or LCT mixed with captan (E2), and in some cases following re-entry in treated field (E3).

Systematic analysis of the relationship between standardized biological levels of polychlorinated biphenyls and thyroid function in pregnant women and newborns.

The impact polychlorinated biphenyl (PCB) exposure on thyroid status in pregnant women and newborns was investigated in various epidemiological studies, but findings show inconsistencies, and differences in biological indicators of exposure between studies limits comparison of results. The aim of this research was to use a procedure previously developed to standardize PCB biological concentration data between published studies to perform a systematic analysis of associations between PCB exposure and thyroid hormones (THs) (total and free T3 and T4) or thyroid stimulating hormone (TSH) in pregnant women and newborns. Biological concentrations from nineteen studies were expressed in total PCB equivalent per kg of lipids in maternal plasma (μg PCBMPEQ kg(-1) lipids).

Systematic analysis of the relationship between standardized prenatal exposure to polychlorinated biphenyls and mental and motor development during follow-up of nine children cohorts.

Impact of prenatal exposure to polychlorinated biphenyls (PCBs) on mental and motor development has been investigated in various children cohorts, but findings show temporal inconsistencies. Because a direct comparison of results obtained from different cohorts remains difficult, temporal relationship between biological PCB concentrations and long-term developmental effects is still not clearly established. The objective of this research was to use a procedure previously developed to standardize PCB biological concentration data across cohorts in order to perform a systematic analysis of temporal associations between prenatal PCB exposure and mental and motor development from neonatal period (or a young age) until school age.

Relationship between prenatal exposure to polychlorinated biphenyls and birth weight: a systematic analysis of published epidemiological studies through a standardization of biomonitoring data.

Impact of prenatal PCB exposure on birth weight was investigated in various children cohorts and findings of published studies show inconsistencies. Because a direct comparison of results obtained from different studies remains difficult, the "biological concentration-birth weight" relationship is not clearly established. The objective of this research was to perform a systematic analysis of published epidemiological data to reassess relationship between prenatal PCB exposure and low birth weight, using toxicokinetic considerations and a novel standardization procedure of biological concentration data across studies.