Elevating Smart Manufacturing with a Unified Predictive Maintenance Platform: The Synergy between Data Warehousing, Apache Spark, and Machine Learning.

The transition to smart manufacturing introduces heightened complexity in regard to the machinery and equipment used within modern collaborative manufacturing landscapes, presenting significant risks associated with equipment failures. The core ambition of smart manufacturing is to elevate automation through the integration of state-of-the-art technologies, including artificial intelligence (AI), the Internet of Things (IoT), machine-to-machine (M2M) communication, cloud technology, and expansive big data analytics. This technological evolution underscores the necessity for advanced predictive maintenance strategies that proactively detect equipment anomalies before they escalate into costly downtime.

Controlling the Selectivity Patterns of Au-Catalyzed Cyclization-Migration Reactions.

As little as 2 mol % of (XPhos)AuNTf catalyzes the transformation of a broad range of o-acetylene-substituted styrenes into 1,2-dihydronaphthalenes. Our data suggests that this transformation occurs via a gold-stabilized cyclopropyl carbinyl cation, which triggers either a [1,2] carboxylate shift or a less favorable [1,2] aryl shift. The relative rates of these migrations can be controlled by the identity of the ligand or by stabilizing the mesomeric cation.

Achieving Site Selectivity in Metal-Catalyzed Electron-Rich Carbene Transfer Reactions from N-Tosylhydrazones.

Catalyst control of the site-selectivity of electron-rich alkyl, aryl disubstituted carbenes generated in situ from o-alkenyl-substituted N-tosylhydrazones was achieved in this study. Exposure of these substrates to copper iodide triggered the formation of α-alkoxy 2H-naphthalenones. This investigation established that changing the catalyst to a rhodium(II) carboxylate turned off cyclization and migration of the electron-rich metal carbene with the β-carboxylate and turned on allylic C-H bond functionalization to diastereoselectively afford 1H-indenes.

Copper-Catalyzed Formation of α-Alkoxycycloalkenones from N-Tosylhydrazones.

The combination of 20 mol % of copper iodide and lithium tert-butoxide triggers the formation of a broad range of substituted, functionalized α-alkoxy 2H-naphthalenones from readily available N-tosylhydrazones. The data suggests that this transformation occurs through cycloaddition of a copper carbenoid with an ester, followed by a Lewis acid-catalyzed [1,2] alkyl shift of the in situ generated alkoxyepoxide intermediate.