Publications by authors named "Naifain Al Kalbani"
Background: Hypertension is prevalent in the pediatric population, with estimated rates between 2% and 5%, and its incidence is rising globally. This study offers a single-center analysis of hypertension in children.
Methods: a retrospective chart review was conducted involving children aged 1 month to 13 years diagnosed with hypertension.
Article Synopsis
- Encapsulating peritoneal sclerosis (EPS) is a serious but rare complication of long-term peritoneal dialysis, notably affecting children with an incidence of 0.5% to 7.3%.
- A 13-year-old boy with end-stage kidney disease from nephrotic syndrome experienced symptoms like abdominal pain and vomiting, leading to a diagnosis of EPS via CT scan after being on automated peritoneal dialysis.
- Following the diagnosis, he switched to hemodialysis, received treatment with steroids and Tamoxifen, and eventually underwent kidney transplantation, which greatly improved his health and quality of life.
Objectives: Atypical hemolytic uremic syndrome (aHUS) is a rare, life-threatening disease of chronic uncontrolled complement pathway activation that leads to thrombotic-microangiopathy, along with severe organ damage, including end-stage kidney disease. This study aimed to evaluate the epidemiology, management, and outcome of aHUS in an Omani population.
Methods: This retrospective descriptive cohort study assessed all cases of aHUS diagnosed and followed up at two tertiary care centers in Oman from January 2008 to December 2019, based on clinical features, complement pathway assays, histopathological, and genetic testing.
Objectives: To determine the spectrum of kidney diseases in Omani children < 13 years of age and to evaluate the complications following kidney biopsy.
Methods: This study retrospectively investigated the hospital data of children who underwent kidney biopsies from January 2014 to June 2019 at Royal Hospital, Muscat, Oman.
Results: The subjects comprised of 78 children with a median age of 8.
Article Synopsis
- Nephrotic syndrome (NS) is a kidney disorder in children characterized by significant protein loss, low blood albumin, swelling, and high cholesterol; while most respond well to steroids, some (10-20%) do not and are at risk for kidney failure.
- A study over 15 years examined 77 Omani children with steroid-resistant nephrotic syndrome (SRNS) to identify genetic causes using advanced sequencing techniques.
- The research uncovered genetic variants in 79.2% of the children, predominantly in NPHS2 and NPHS1 genes, suggesting these should be targeted for screening to improve management and counseling for families affected by SRNS.
Objectives: This study aimed to explore high school students' awareness and attitude towards premarital screening (PMS).
Methods: This cross-sectional study was conducted in 10 public high schools in Muscat, Oman from May to July 2016. A three-part self-administered questionnaire was used to collect data from grade 12 students.
Objectives: This study sought to report 22 years experience in pediatric kidney transplantation in Oman.
Methods: Electronic charts of all Omani children below 13 years of age who received a kidney transplant from January 1994 to December 2015 were reviewed. Data collected included patient demographics, etiology of end-stage kidney disease, modality and duration of dialysis, donor type, complication of kidney transplantation (including surgical complications, infections, graft rejection) graft and patient survival, and duration of follow-up.
Background. Primary hyperoxaluria belongs to a group of rare metabolic disorders with autosomal recessive inheritance. It results from genetic mutations of the AGXT gene, which is more common due to higher consanguinity rates in the developing countries.
View Article and Find Full Text PDFA case of a six-year-old boy presenting with gross hematuria is reported. Investigations revealed the etiology of the hematuria to be thrombocytopenia in the setting of newly diagnosed acute lymphoblastic leukemia. The diagnosis of leukemia was confirmed by bone marrow examination.
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