Wogonin suppresses proliferation and invasion of skin epithelioid carcinoma cells through Notch1.

The current study was carried out to investigate the role of wogonin in proliferation and invasion of skin epithelioid carcinoma cells as well as its underlying mechanisms. For this purpose, skin epithelioid carcinoma cells were treated with 0, 5, 10 and 20μmol/L wogonin for 24, 48, 72 hours. Cell proliferation was evaluated by an MTT assay.

[Preparation of low immunogenic porcine dermal scaffold and evaluation of its cytocompatibility].

Objective: To observe the changes in the structure and cytocompatibility of porcine acellular dermal matrix, which was prepared with dermal reticular layer, treated with matrix metalloproteinase 7 (MMP-7), genipin, and vacuum freeze-drying.

Methods: Fifty-four pieces of porcine dermal reticular layer, prepared with lateral abdominal skin were obtained from healthy large Yorkshire pig with mechanical method under sanitary condition, each 10.0 mm×5.