Publications by authors named "Nai-Quan Mao"
Article Synopsis
- - The study evaluated the effectiveness of lymph node ratio (LNR) versus pN in predicting outcomes for patients with non-small cell lung cancer (NSCLC) who had surgery, using data from 2004 to 2015.
- - It identified LNR cut-off values of 0.19 and 0.73, revealing that patients with lower LNR (LNR1) had significantly longer cancer-specific survival (CSS) and overall survival (OS) compared to those with higher LNR values (LNR2 and LNR3).
- - The research concluded that a revised pN classification that includes LNR offers better predictive accuracy for CSS and OS, suggesting that LNR may be a more effective tool for
Article Synopsis
- - The study investigated the impact of postoperative radiotherapy (PORT) on patients with pIIIA-N2 non-small cell lung cancer following surgery and chemotherapy.
- - Researchers analyzed data from three high-quality randomized control trials involving 902 patients, comparing the effects of PORT with observation.
- - Findings indicated that while PORT significantly reduced local recurrence rates, it had no significant effect on disease-free survival (DFS) or overall survival (OS).
Expert consensus on resection of chest wall tumors and chest wall reconstruction.
Transl Lung Cancer Res
November 2021
Chest wall tumors are a relatively uncommon disease in clinical practice. Most of the published studies about chest wall tumors are usually single-center retrospective studies, involving few patients. Therefore, evidences regarding clinical conclusions about chest wall tumors are lacking, and some controversial issues have still to be agreed upon.
View Article and Find Full Text PDFObjective: To observe the effect of transcutaneous electrical acupoint stimulation (TEAS) on venous thrombosis and quality of life after lung cancer surgery, basing on the conventional nursing and early functional exercise.
Methods: A total of 120 patients diagnosed as non-small cell lung cancer (NSCLC) and received radical resection of lung cancer surgery for the first time were randomized into a conventional nursing group, a rehabilitation training group and a TEAS group, 40 cases in each group. Conventional nursing was adopted in the conventional nursing group.
An association between epidermal growth factor receptor (EGFR) and clinical characteristics of non-small cell lung cancer (NSCLC) was reported ten years ago. In addition, a different type of relationship was seen in different ethic races. However, the relationship between these factors is not well understood in the Guangxi province.
View Article and Find Full Text PDFObjective: To assess if casticin induces caspase-mediated apoptosis via activation of mitochondrial pathway and upregulation of DR5 in human lung cancer cells.
Methods: Human non-small-cell lung carcinoma cell lines H460, A549 and H157 were cultured in vitro. The cytotoxic activities were determined using MTT assay.
[Isolation and identification of side population cells in human lung adenocarcinoma cell line A549].
Zhonghua Zhong Liu Za Zhi
February 2011
Objective: To isolate and characterize the side population cells (SP cells) in the lung adenocarcinomas cell line A549.
Methods: The protein expression of ABCG2 in human lung adenocarcinoma cell line A549 was detected by immunohistochemistry. SP and NSP cells in the cell line A549 were isolated by FACS, and their differentiation was analysed.
Objective: To evaluate the relationship between combined multigene detection and response to adjuvant chemotherapy and prognosis in early-stage non-small cell lung cancer (NSCLC).
Methods: Tissue microarray was prepared from samples of 86 cases of early-stage NSCLC who received adjuvant chemotherapy after radical surgery. The expressions of caspase-3, Fas, bax, bcl-2, survivin, PCNA, Ki67, MGMT, p53, p63, p73, p16, p27, VEGF, nm23, P-gp, MRP, LRP, GST-pi, Topo II, c-myc, cyclin-D1, Her-2, Cox-2, Ku70, Ku80, DNA-PKcs, ERCC1, MSH2, BCRP proteins were detected using immunohistochemical two-step method.