Publications by authors named "Nai-Lang Lai"
Background: Mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) in non- small cell lung cancer (NSCLC) are predictive of response to EGFR-targeted therapy in advanced stages of disease. This study aimed to determine the frequency of EGFR mutations in NSCLCs and to correlate their presence with clinical characteristics in multiethnic Malaysian patients.
Materials And Methods: In this prospective study, EGFR mutations in exons 18, 19, 20 and 21 in formalin-fixed paraffin-embedded biopsy specimens of consecutive NSCLC patients were asessed by real-time polymerase chain reaction.
Article Synopsis
- - A pregnant woman in her third trimester experienced respiratory failure caused by a right-sided pleural effusion, lung metastases, and lymphangitis carcinomatosis related to advanced lung adenocarcinoma.
- - The patient's condition involved severe complications from the cancer impacting her lungs and pleura, leading to respiratory issues.
- - Treatment with an EGFR tyrosine kinase inhibitor resulted in a positive response, helping to improve her health condition.