Effect of resistance training on non-alcoholic fatty-liver disease a randomized-clinical trial.

Aim: To evaluate the effect of resistance training (RT) on non alcoholic liver disease (NAFLD) patients.

Methods: A randomized clinical trial enrolling NAFLD patients without secondary liver disease (e.g.

Body composition in untreated adult patients with Laron syndrome (primary GH insensitivity).

Objective: To quantify body adiposity and its distribution in untreated adult patients with Laron syndrome (LS; primary GH insensitivity) caused by molecular defects of the GH receptor gene or postreceptor pathways and characterized by dwarfism, obesity, insulin resistance and hyperlipidaemia.

Patients: Eleven LS patients (seven females and four males) aged 28-53 years were studied. Seven healthy males and six healthy females served as controls.

Long-term IGF-I treatment of children with Laron syndrome increases adiposity.

Laron syndrome (LS) is an autosomal recessive disease caused by deletions or mutations in the GH receptor gene leading to an inability of insulin-like growth factor I (IGF-I) generation. Among the major resulting body changes are dwarfism and obesity. The only effective treatment is daily administration of biosynthetic IGF-I.