Publications by authors named "Naho Akada"
Article Synopsis
- The study explores new methods for enantioselective bromolactonization of trisubstituted olefinic acids, which produce chiral lactones with two asymmetric centers.
- This research highlights the successful application of 5-exo and 6-endo bromocyclization using N-bromosuccinimide and a pyridyl phosphoramide catalyst for the first time.
- It also reveals how factors such as the basicity of pyridine and the presence of N-H protons in the catalyst significantly impact the reactivity and enantioselectivity of the reactions.
