Antibacterial Lecithin/Chitosan Nanoparticles for the Sustained Release of Ciprofloxacin to Treat Ocular Bacterial Infections.

Ocular drug-delivery is one of the most challenging areas owing to nature of ocular tissues. Various nanoformulations have been designed and investigated for drug-delivery to achieve high drug bioavailability. The major focus of these preparations available in market is to utilize nanomaterial as drug-carrier only, with less focus on developing functional-nanomaterials, which is a key knowledge gap in the field.

Thiol-Functionalized, Antioxidant, and Osteogenic Mesoporous Silica Nanoparticles for Osteoporosis.

Osteoporosis is a chronic bone disorder characterized by decreased bone mass, leading to brittle bones and fractures. Oxidative stress has been identified as the most profound trigger for the initiation and progression of osteoporosis. Current treatment strategies do not induce new bone formation and fail to address a high level of reactive oxygen species (ROS).

Cationized silica ceria nanocomposites to target biofilms in chronic wounds.

Altered wound healing is a major challenge faced by both developed and developing nations. Biofilm formation has been identified as one of the causative factors for the progression of chronic wounds. The spread of biofilm is controlled by inhibiting the biofilm formation or disrupting the mature biofilm.