Publications by authors named "Nahawand A El-Deeb"
Background: The clinical presentations of coronavirus disease 2019 (COVID-19) exhibit significant variation, ranging from asymptomatic cases to mortality resulting from severe pneumonia. Host genetics can partially explain this variation.
Objective: This study evaluated possible associations between severity and outcome of COVID-19 and single nucleotide polymorphism (SNP) rs2285666 in the gene and SNP rs2070788 in the gene.
Article Synopsis
- Mucormycosis has emerged as a serious fungal infection following COVID-19, raising concerns about mortality risk factors in affected patients.
- A study tracked 150 post-COVID-19 mucormycosis patients in the ICU from May 2021 to April 2022, revealing that 21% died, often linked to pneumonia and pulmonary embolism.
- Key risk factors for increased mortality included age over 60, steroid use, facial infections, uncontrolled diabetes, and high leukocyte counts.
Background: Given the sparse data on the renin-angiotensin system (RAS) and its biological effector molecules ACE1 and ACE2 in pediatric COVID-19 cases, we investigated whether the ACE1 insertion/deletion (I/D) polymorphism could be a genetic marker for susceptibility to COVID-19 in Egyptian children and adolescents.
Methods: This was a case-control study included four hundred sixty patients diagnosed with COVID-19, and 460 well-matched healthy control children and adolescents. The I/D polymorphism (rs1799752) in the ACE1 gene was genotyped by polymerase chain reaction (PCR), meanwhile the ACE serum concentrations were assessed by ELISA.
Background: Egypt was among the first 10 countries in Africa that experienced COVID-19 cases. The sudden surge in the number of cases is overwhelming the capacity of the national healthcare system, particularly in developing countries. Central to the containment of the ongoing pandemic is the availability of rapid and accurate diagnostic tests that could pinpoint patients at early disease stages.
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