Publications by authors named "Naharmal B Soni"
Article Synopsis
- A pilot study was conducted to evaluate the effectiveness of noradrenaline versus adrenaline in treating neonatal septic shock at a NICU from August 2020 to January 2022.
- Key findings showed that after one hour, 76.2% of neonates in the noradrenaline group had resolution of shock compared to 61.9% in the adrenaline group, with similar mortality rates of 28.6% and 33.3%, respectively.
- Additionally, the noradrenaline group required fewer additional vasopressors and had a shorter median ICU stay (6 days) compared to the adrenaline group (10 days).
Background: The incidence of neonatal septic shock in low-income countries is 26.8% with a mortality rate of 35.4%.
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- - The study compared the effectiveness and safety of oral versus intravenous sildenafil in treating mild to moderate pulmonary hypertension in newborns, particularly in areas without access to inhaled nitric oxide.
- - Conducted as a randomized trial in a neonatal intensive care unit in India, the research involved 40 newborns and measured various health outcomes, including pulmonary arterial pressure and oxygenation index.
- - Results showed no significant difference in the time taken to reduce pulmonary arterial pressure between the two groups, though systemic hypotension was observed in some infants receiving intravenous sildenafil, which was not seen in the oral group.
Article Synopsis
- Mechanical ventilation can save the lives of critically ill newborns but may also harm their lungs and lead to long-term issues.
- It's crucial for healthcare providers to understand how both conventional and high-frequency ventilation work in order to manage neonatal respiratory needs effectively.
- The review discusses different ventilation types used in neonatal care and suggests personalized strategies based on specific diseases for better patient outcomes.
Article Synopsis
- - Mechanical ventilation is crucial for neonatal patients with respiratory failure, as it helps ensure proper oxygen delivery and carbon dioxide excretion.
- - Advanced techniques like volume-targeted ventilation have been developed for very premature infants, allowing for precise control of airflow and tidal volumes.
- - A solid grasp of respiratory physiology and the specific disease mechanisms is essential for selecting appropriate ventilation modes and settings to enhance gas exchange while minimizing lung damage.
Objective: To assess the feasibility and effectiveness of pulse-oximetry as a screening tool in the detection of critical congenital heart disease (CCHD) in newborns.
Methods: Post-natal babies born between 01/01/2007-31/12/2009 were eligible. Post-ductal pulse-oximetry was performed using Nellcor® NPB 40 pulse oximeter with reusable OXI-A/N saturation probe.