Profiling of two species using LC-ESI/MS with evidence of their hepatoprotective activity.

and are only reported to have significant cytotoxic activity against certain cancer cell lines with phytochemical investigation of their petroleum ether and the ethyl acetate extracts. Further investigation was suggested concerning their hepatoprotective activity and relating it to the metabolic profile of their defatted methanol extracts using LC-ESI/MS analysis. Hepatoprotective activity was evaluated through assessment of three liver parameters as well as liver histopathological examination in thioacetamide-induced hepatotoxicity model.

Structural characterization of three cytotoxic steroidal saponins from the leaves of Agave desmetiana hort.

Three steroidal saponins detected by LC-MS were isolated from the leaves of Agave desmetiana hort. The three saponins were characterized as; Tigogenin 3 - [{O - β - D - xylopyranosyl (1 → 2) - α - L-rhamnopyranosyl (1 → 3)}-β-D- glucopyranoside), Tigogenin- 3 - ([O- α -L-rhamnopyranosyl (1 → 3) - β - D - glalactopyranosyl (1 → 2)] - β - D - glucopyranoside) and Tigogenin- 3 - ([{O - α - L - rhamnopyranosyl (1 → 4)} - β - D - galactopyranosyl (1 → 3) - β - D - xylopyranosyl (1 → 2)] - β - D - glucopyranoside). Identification and structure elucidation of the isolates were done via 1D and 2D NMR techniques, and chemical methods.

Phytochemical investigation of and family Aizoaceae and evaluation of their cytotoxic activity.

This study aims to shed light on the phytochemical composition and the biological effect of two members of family and Gas chromatography coupled to mass spectrometry (GC-MS) and high-performance liquid chromatography (HPLC) was used to investigate the lipoidal matter and the phenolic content, respectively. The MTT assay was used to evaluate the cytotoxic activity against MCF-7 (breast cancer), HepG2 (liver cancer) and HCT-116 (colorectal cancer) cell lines. The total phenolic acids and the total flavonoid content of were found to be higher than that of Phytol, hexadecanoic acid, -coumaric, ferulic and - hydroxybenzoic acids were the major detected compounds.

The anti-inflammatory, anti-ulcer activities and phytochemical investigation of L. cv. Ismailawi fruits.

This study aims to evaluate the anti-inflammatory and anti-ulcer activities of L. cv. Ismailawi fruits, as well as the investigation of the phenolic content and lipoidal matter composition via high performance liquid chromatography and gas chromatography coupled to mass spectrometry respectively.

Anti-Alzheimer potential, metabolomic profiling and molecular docking of green synthesized silver nanoparticles of Lampranthus coccineus and Malephora lutea aqueous extracts.

The green synthesis of silver nanoparticles (SNPs) using plant extracts is an eco-friendly method. It is a single step and offers several advantages such as time reducing, cost-effective and environmental non-toxic. Silver nanoparticles are a type of Noble metal nanoparticles and it has tremendous applications in the field of diagnostics, therapeutics, antimicrobial activity, anticancer and neurodegenerative diseases.

Antiviral potential of green synthesized silver nanoparticles of and .

Background: Viral and microbial infections constitute one of the most important life-threatening problems. The emergence of new viral and bacterial infectious diseases increases the demand for new therapeutic drugs.

Purpose: The objective of this study was to use the aqueous and hexane extracts of and F.