Genus L.: a newly explored sustainable source of virulence inhibitors: a mini review.

Misuse of antibiotics led to the world wide spread of antimicrobial resistance threatening human lives. The notable resistance of bacterial cells to antibiotics and immune system is the difficulty associated with biofilm-linked illnesses. Natural products from plant origin with antibiofilm activity could provide more therapeutic activity with fewer adverse effects.

Metabolomic study of the estrogenic and anti-osteoporotic potential of Erythrina bidwillii leaf.

Erythrina bidwillii Lindl., Leguminosae, constitutes a valuable crop for horticulture and medicine; however, it is rarely investigated. Menopause is a crucial transitional period in women's health.

Sulawesins A-C, Furanosesterterpene Tetronic Acids That Inhibit USP7, from a Psammocinia sp. Marine Sponge.

Three new furanosesterterpene tetronic acids, sulawesins A-C (1-3), were isolated from a Psammocinia sp. marine sponge, along with the known compounds ircinins-1 (4) and -2 (5). Although ircinins-1 and -2 were previously isolated as (+)- or (-)-enantiomers from marine sponges, we isolated them as enantiomeric mixtures.

Different modalities for treatment of recurrent aphthous stomatitis. A Randomized clinical trial.

Background: The underlying etiology of recurrent aphthous stomatitis (RAS) is unclear and treatment aims to provide symptomatic and faster relief. This study compared the efficacy of diode laser, a herbal combination of Acacia nilotica and Licorice (A and L) and Amlexanox in the management of RAS.

Material And Methods: Sixty patients with minor aphthae were selected and randomly divided into four groups of 15 each.

Boswellia carterii liquisolid systems with promoted anti-inflammatory activity.

(BC) Birdwood oleogum resin is an ancient remedy of inflammation processes known since Ancient Egyptian time. Of boswellic acids, 3-acetyl-11-keto-β-boswellic acid (AKBA) is the most potent anti-inflammatory active principle. Liquisolid systems of the biologically active fraction of BC oleogum resin were prepared for improving dissolution properties using low dose oral delivery to achieve enhanced anti-inflammatory activity, in comparison with the standard oral anti-inflammatory; Indomethacin.

Phytochemical and biological studies of Butia capitata Becc. leaves cultivated in Egypt.

Objective: To study the antioxidant and anti-inflammatory activity of Butia capitata (B. capitata) leaf extracts along with phytochemical analysis of the proposed bioactive constituents.

Methods: Different successive extracts of B.

Transdermal microemulsions of Boswellia carterii Bird: formulation, characterization and in vivo evaluation of anti-inflammatory activity.

Context: Boswellia species are trees (family: Bruseraceae) found in India, Northern Africa and the Middle East.

Objective: This study aims at formulating low dose biologically active fraction from the oleogum resin of Boswellia carterii (BC) in transdermal (TD) microemulsions (MEs) to acquire promoted anti-inflammatory efficacy.

Materials And Methods: The bioactive fraction of the oleogum resin of BC was tested for solubility in different components.

Transdermal microemulsions of Glycyrrhiza glabra L.: characterization, stability and evaluation of antioxidant potential.

The purpose of the present study is to formulate Glycyrrhiza glabra root and rhizome aqueous ethanolic extract in microemulsion carrier systems intended for transdermal delivery of incorporated antioxidant actives, flavonoids and polyphenols. The results obtained reveal that the microemulsion system ME3 possesses optimum properties regarding drug content (flavonoids and polyphenols), viscosity, pH, particle size and polydispersity index, zeta potential, stability, permeation of actives and hence possesses high in vitro and ex vivo antioxidant efficacy. These results indicate also that this microemulsion shows approximately 13-fold higher ex vivo antioxidant capacity compared with the liquorice extract solution.

Effect of Ruta graveolens L. and Euphorbia peplus L. anti-inflammatory extracts on nutritional status of rats and the safety of their use.

A significant increase in body weight with remarkable increase in total food intake and significant increase in protein efficiency ratio were observed following oral administration of R. graveolens ether extract (500 mg/kg body wt) to growing rats for 3 weeks. Serum albumin was significantly decreased after administration of declofenac (15 mg/kg body wt).