Impact of vitamin D on COVID-19 and other viral diseases.

This editorial aims to elucidate the intricate relationship between vitamin D and viral pathogenesis. It explores the anticipated role of vitamin D as a modulator in the immune response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other viral pathogens. The editorial comments are based on the review article by Engin .

Understanding serum inflammatory markers in pediatric pneumonia.

This editorial reflects on the research, which investigates the potential of serum markers to predict the severity of infections. pneumonia (MPP) is a prevalent cause of respiratory infections in children, often leading to significant morbidity. Predicting the severity of MPP can significantly enhance patient management and outcomes.

Multi-systemic melioidosis.

This editorial is a commentary on the article by Ni which was published in the . The article discusses the diagnostic and therapeutic challenges of melioidosis caused by . The case study highlights a rare instance of multisystemic melioidosis in a female patient who did not have a travel history, emphasizing the significance of recognizing this condition in non-endemic regions.

Hepatitis E virus infections.

Hepatitis E virus (HEV) infection is now endemic worldwide. Most patients with acute infection recover uneventfully. Outbreaks and sporadic cases, particularly in high-risk individuals are emerging increasingly.

A critical review of risk factors influencing the prevalence of extensive drug-resistant tuberculosis in India.

Globally, extensive drug-resistant tuberculosis (XDR-TB) is a major element to cause morbidity and death among tuberculosis patients. The present study identifies the vital risk variables contributing to XDR-TB prevalence in India. Scopus, PubMed/Medline, Science Direct, and Google Scholar databases were searched thoroughly for the articles, using medical subject heading as a key term published between the years 2012 and 2022.

Current scenario of traditional medicines in management of diabetic foot ulcers: A review.

Diabetic foot infections and diabetic foot ulcers (DFU) cause significant suffering and are often recurring. DFU have three important pathogenic factors, namely, microangiopathy causing local tissue anoxia, neuropathy making the foot prone to injuries from trivial trauma, and local tissue hyperglycaemia favouring infection and delaying the wound healing. DFU have been the leading cause for non-traumatic amputations of part or whole of the limb.

COVID-19 associated diabetes mellitus: A review.

A significantly higher rate of new-onset diabetes in many coronavirus disease 2019 (COVID-19) patients is a frequently observed phenomenon. The resultant hyperglycemia is known to influence the clinical outcome, thereby increasing the cost of treatment and stay in hospital. This will also affect the post-hospitalization recuperation.

Citric acid treatment of a diabetic leg ulcer infected with meticillin-resistant .

Diabetic leg ulcers are difficult to manage. Infection by bacterial pathogens, such as meticillin-resistant (MRSA), is one of the most important reasons for non-healing of ulcers. If not treated in a timely manner, the ulceration may progress to septicaemia, amputation and even death.

Retrograde Intussusception of Distal Limb of Loop Ileostomy: A Rare Case Report and Review of Literature.

Stoma related complications affect the quality of life and may require another intervention for correction. Intussusception of either limb through a stoma is a rare complication which can be easily missed. Delay in presentation and diagnosis complicates the matter, necessitates laparotomy and resection of more bowel, ultimately increases the morbidity of the patient.

Positive Aspects, Negative Aspects and Challenges Associated with Stem Cell Therapy for COVID - 19: A Mini-review.

Like any other pandemic, Covid-19 scenario has also demanded effective treatment options. The circumstances demand to utilize all the possible weapons in the armamentarium. There have been many issues regarding the short-term and long-term safety and efficacy of these options.

Role of an acidic environment in the treatment of diabetic foot infections: A review.

Management of diabetic foot ulcers is the biggest challenge to the clinician, as conventional antibiotic therapies and local wound care have their own limitations. They are not effective for control of infections and promotion of healing because of cytotoxic effects. In view of cytotoxicity of routinely used topical antiseptic agents, this article focuses on the search of an ideal topical antiseptic agent that is safe and effective in controlling infectious agents and also in promoting the healing process.

Using Topical Citric Acid to Treat an Infected Ulcerated Hemangioma in an Infant: A Case Study.

Infantile hemangiomas (IHs) are the most common vascular abnormalities in children under 1 year old; most IHs involute spontaneously and do not need intervention unless a complication occurs. Ulceration and secondary infection are the most common complications. Despite appropriate conventional wound care, ulcerated IHs are difficult to heal.

Positive aspects, negative aspects and limitations of plasma therapy with special reference to COVID-19.

The principle of plasma therapy can be used for prophylaxis and treatment purpose. In view of non-availability of suitable vaccine for prevention or no established definitive therapy for SARS-CoV-2, plasma therapy is gaining importance in a current pandemic as one of the treatment options for the treatment of COVID-19. Although, it has been reported to be an effective approach in various preliminary studies, convalescent plasma (CP) therapy has several limitations.

Studies on wound healing potential of topical herbal formulations- do we need to strengthen study protocol?

Healing of wound is a normal biological process that occurs naturally as long as it is not obstructed by infection. Many monoherbal and polyherbal formulations have been reported to hasten/accelerate wound healing activity in freshly prepared incisional and excisional experimental wound models. In the present review, an attempt has been made to throw light on importance of microbial infection in the process of wound healing and antimicrobial activity of herbal formulations.

Citric acid treatment of oral ulcers refractory to conventional treatment: a case study.

Oral ulcers are painful sores that appear in the mouth. Most of them are usually harmless and clear up on their own. Sometimes, they are non-responsive and difficult to manage.

Profile and Antibiotic Susceptibility of Bacterial Pathogens Associated With Diabetic Foot Ulcers From a Rural Area.

Objective: This cross-sectional study assesses the profile and antibiotic susceptibility of aerobic bacterial pathogens associated with diabetic foot ulcers (DFUs).

Materials And Methods: Two swab samples from 140 DFUs with various Wagner grades were processed for identification using routine culture methods and antimicrobial susceptibility by Kirby-Bauer disc diffusion method.

Results: A total of 125 (89.

Assessment of periodontitis and its role in viridans streptococcal bacteremia and infective endocarditis.

Objectives: To evaluate the role of periodontitis in viridans group streptococci (VGS) bacteremia and infective endocarditis (IE).

Methods: A total of 200 subjects including two groups. Group A- 34 subjects undergoing tooth extraction with periodontitis, 46 subjects undergoing tooth extraction without periodontitis and 40 healthy controls.