Hydrogen cyanide poisoning: treatment with cobalt EDTA.

Three case reports are presented of employees who suffered varying degrees of exposure to hydrogen cyanide and their subsequent clinical courses following treatment with cobalt EDTA. A review of treatment modalities for CN- toxicity is given. It is concluded that, because of the degree of patient symptomatology associated from the use of cobalt EDTA, this therapy be reserved only for patients with the most severe degress of exposure to CN(-), and that in all other cases combined sodium nitrite and sodium thiosulphate therapy should be employed.

Metastatic colon carcinoma simulating primary bile duct carcinoma via endoscopic cholangiography.

A case of metastatic colon carcinoma simulating primary bile duct carcinoma is presented. The radiographic similarities via endoscopic retrograde cholangiopancreatography include bile duct narrowing and mucosal destruction. A distinguishing feature, however, is failure of the intrahepatic bile ducts to dilate in metastatic carcinoma to the biliary tree.