Publications by authors named "Nagib Dally"
Solitary plasmacytoma (SP) is a rare plasma cell dyscrasia. In this retrospective multicenter study, 68 SP patients were included. Compared to solitary extramedullary plasmacytoma (SEP), patients with solitary bone plasmacytoma (SBP) were younger (57.
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- * Out of 313 patients, 36% experienced severe respiratory infections, 61% were hospitalized, and 20% died, with older age and hypertension linked to worse outcomes.
- * Among treatments, only remdesivir significantly reduced mortality, while other therapies like convalescent plasma and corticosteroids showed no clinical benefit.
Article Synopsis
- * Results showed a 61% overall response rate, with 40% achieving complete responses and a median overall survival of 8.3 months, indicating positive outcomes for this treatment.
- * Factors like poor Eastern Cooperative Oncology Group performance status and primary refractory disease were linked to shorter survival and progression-free survival, highlighting their impact on treatment outcomes.