High complement factor I activity in the plasma of children with autism spectrum disorders.

Autism spectrum disorders (ASDs) are neurodevelopmental and behavioural syndromes affecting social orientation, behaviour, and communication that can be classified as developmental disorders. ASD is also associated with immune system abnormality. Immune system abnormalities may be caused partly by complement system factor I deficiency.

Alterations of prolyl endopeptidase activity in the plasma of children with autistic spectrum disorders.

Background: Prolyl Endopeptidase (PEP, EC 3.4.21.