Publications by authors named "Nageshwar Kothur"
Objectives: The healthcare industry is grappling with escalating expenses, partially attributed to the inefficient use of medical resources, particularly by ordering unnecessary laboratory tests. Such practices not only increase costs but also result in extended hospital stays, patient discomfort, and potential clinical complications such as iatrogenic anemia. Blood tests, although essential for guiding medical decisions, are associated with significant clinical and financial costs.
View Article and Find Full Text PDF3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitors are commonly used drugs in the management of elevated lipid levels and cardiovascular disease. In cardiovascular diseases, among other common chronic conditions, inflammatory biomarkers are used to monitor disease progression and the risk of recurrent adverse events. We explored whether or not there was a positive effect on these biomarkers using HMG-CoA reductase inhibitors.
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- Rheumatoid arthritis (RA) is a chronic and destructive arthritis condition primarily affecting women, leading to joint damage and significant inflammation that can impair physical and mental health over time.
- A systematic review was conducted using multiple databases to explore how increased physical activity and exercise influence cognitive abilities in RA patients, focusing on 12 high-quality studies.
- The findings indicate that regular physical activity and aerobic exercise improve overall well-being, reduce inflammation, and enhance cognitive function in RA patients, highlighting the need for better patient counseling and future research to boost quality of life.
Hypertrophic cardiomyopathy (HCM) is a genetically acquired disease of cardiac myocytes. Studies show that 70% of this disease is a result of different mutations in various sarcomere genes. This review aims to discuss several genetic mutations, epigenetic factors, and signal transduction pathways leading to the development of HCM.
View Article and Find Full Text PDFDigital microscopy (DM) is one of the cutting-edge advances in pathology, which entails improved efficiency, diagnostic advantages, and potential application in virtual diagnosis, particularly in the current era of the coronavirus disease (COVID-19) pandemic. However, the diagnostic challenges are the remaining concerns for its wider adoption by pathologists, and these concerns should be addressed in a specific subspecialty. We aim to identify the common diagnostic pitfalls of whole slide imaging (WSI), one modality of DM, in gastrointestinal (GI) pathology.
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