A comparative study of passive drug diffusion through human skin via intercellular and sweat duct route: effect of aging.

A method of drug delivery that could provide control over medicine reaching the bloodstream for systemic circulation would be of immense importance. This work presents a comparative study of the temporal and spatial variation of drugs diffusing passively through two separate routes of human skin, namely intercellular (ICR) and sweat duct route (SDR). An analysis is carried out for two age groups (young < 40 years and old > 60 years of age).

Pinning and Depinning Dynamics of an Evaporating Sessile Droplet Containing Mono- and Bidispersed Colloidal Particles on a Nonheated/Heated Hydrophobic Substrate.

The present study is primarily focused on the coupled effects of substrate heating, colloidal dispersion, and particle size variation on the contact line (CL) pinning-depinning dynamics of evaporating droplets containing mono- (3/4.5 μm) and bidispersed (3 and 4.5 μm) polystyrene colloidal particles on poly(dimethylsiloxane) (PDMS) substrates.

Self-Sorting of Bidispersed Colloidal Particles Near Contact Line of an Evaporating Sessile Droplet.

Here, we investigate deposit patterns and associated morphology formed after the evaporation of an aqueous droplet containing mono- and bidispersed colloidal particles. In particular, the combined effect of substrate heating and particle diameter is investigated. We employ high-speed visualization, optical microscopy, and scanning electron microscopy to characterize the evaporating droplets, particle motion, and deposit morphology, respectively.

Droplet Bouncing and Breakup during Impact on a Microgrooved Surface.

We experimentally investigate the impact dynamics of a microliter water droplet on a hydrophobic microgrooved surface. The surface is fabricated using photolithography, and high-speed visualization is employed to record the time-varying droplet shapes in the transverse and longitudinal directions. The effect of the pitch of the grooved surface and Weber number on the droplet dynamics and impact outcome are studied.

Effects of Substrate Heating and Wettability on Evaporation Dynamics and Deposition Patterns for a Sessile Water Droplet Containing Colloidal Particles.

Effects of substrate temperature, substrate wettability, and particle concentration are experimentally investigated for evaporation of a sessile water droplet containing colloidal particles. Time-varying droplet shapes and temperature of the liquid-gas interface are measured using high-speed visualization and infrared thermography, respectively. The motion of the particles inside the evaporating droplet is qualitatively visualized by an optical microscope and the profile of the final particle deposit is measured by an optical profilometer.

Full mouth rehabilitation of severe fluorozed teeth with an interdisciplinary approach (6 handed dentistry).

Whenever the treatment revolves around structural balance and aesthetic harmony, the crux remains to be the periodontal health of the existing dentition. In such scenarios where restorations and aesthetics are of concern, biologic width (BW) is the initial and final frontier. Considering attrition of teeth, the resistance which is offered by them is definitely at a lower level as compared to teeth with adequate height.

Evaluation of shear bond strength of three different types of artificial teeth to heat cure denture base resin: an in vitro study.

Context: Bonding of artificial teeth and denture base material remained a significant problem for successful prosthetic treatment.

Aim: The purpose of this in vitro study was to evaluate shear bond strength of three different artificial teeth with heat cure denture base material after various surface conditioning methods and thermocycling.

Materials And Methods: Ninety mandibular first molar denture teeth were selected.