Publications by authors named "Nagesh H Aloorkar"
Aim: To evaluate antioxidant activity, DNA damage inhibition and hepatoprotecitve potential of polyherbal formulation Tritone (Livosone).
Methods: In vitro antioxidant activity of Tritone formulation was performed by using DPPH assay. Hepatoprotecitve potential of Tritone was evaluated against various hepatotoxic agents including Paracetamol (2g/kg b.
The motive behind present work was to formulate and evaluate gel containing microsponges of diclofenac diethylamine to provide prolonged release for proficient arthritis therapy. Quasi-emulsion solvent diffusion method was implied using Eudragit RS-100 and microsponges with varied drug-polymer ratios were prepared. For the sake of optimization, diverse factors affecting microparticles physical properties were too investigated.
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- The study focused on creating a new cream with microsponges of miconazole nitrate to achieve a longer-lasting release of the medication.
- Microsponges were made using a special method with a polymer called Eudragit RS-100, and various formulations were tested for their physical characteristics and efficiency.
- Results showed that the microsponges had a mean size of 26.23 μm and released 78.28% of the drug over 8 hours, outperforming traditional formulations which released 83.09% in just 4 hours, suggesting this cream could be a better option for treating acne and skin infections.