"Research paper mills": A factory outlet for dubious research.

The primary objective of any research, regardless of its domain such as health, technology, psychology, or any other subject, is to enhance the overall well-being of individuals. Rigorous processes are involved in conducting research ethically and in communicating its outcomes to society. However, as publishing research has become a mandatory requirement for career advancement and appointments, academics are resorting to several unethical practices to get substandard work published quickly.

The art and science of research methodology, biostatistics, manuscript writing, and publication ethics: An invigorating training for improving research aptitudes in southern Indian biomedical institutions.

The basic concepts of research are learned through systematic literature searches which form the basis of a research statement and research topic. Then the research question, hypothesis, aim, and objectives, as well as the experimental design, are developed. Given the context provided, the primary focus is on the importance of adequately training postgraduates and young research investigators in research methodology and project development.

High Hybrid Mie-Plasmonic Resonances in van der Waals Nanoantennas on Gold Substrate.

Dielectric nanoresonators have been shown to circumvent the heavy optical losses associated with plasmonic devices; however, they suffer from less confined resonances. By constructing a hybrid system of both dielectric and metallic materials, one can retain low losses, while achieving stronger mode confinement. Here, we use a high refractive index multilayer transition-metal dichalcogenide WS exfoliated on gold to fabricate and optically characterize a hybrid nanoantenna-on-gold system.

ChatGPT: Impact of an artificial author on bibliometrics.

The use of Artificial Intelligence (AI) in medical science has been widely discussed and debated. Topol foresaw that AI, particularly deep learning, would be used in a variety of applications, with users ranging from specialty doctors to paramedics [1]. He discussed how deep neural networks (DNNs) of AI can help interpret medical scans, pathology slides, skin lesions, retinal images, electrocardiograms, endoscopy, faces, and vital signs.

Therapeutic mammoplasty: a "wise" oncoplastic choice-lessons from the largest single-center cohort from Asia.

Introduction: The majority of breast cancer patients from India usually present with advanced disease, limiting the scope of breast conservation surgery. Therapeutic mammoplasty (TM), an oncoplastic technique that permits larger excisions, is quite promising in such a scenario and well suited to breast cancer in medium-to-large-sized breasts with ptosis and in some cases of large or multifocal/multicentric tumors. Here, we describe our TM cohort of 205 (194 malignant and 11 benign) patients from 2012 to 2019 treated at a single surgeon center in India, the largest Asian dataset for TM.

Evidence-based fact checking for selective procedures in restorative dentistry.

Objectives: Similar to other dental specialties, there are many clinical procedures in restorative dentistry that may or may not be supported by good evidence. Thus, the effectiveness of these procedures is uncertain. The aim of this paper is to reduce this knowledge gap by critically inspecting selective procedures in restorative dentistry and exploring if these well-established or widely advocated treatment modalities are necessary for improving treatment outcomes based on the best available evidence.

Burden of COVID-19 and case fatality rate in Pune, India: an analysis of the first and second wave of the pandemic.

Objective: To assess trends in case incidence and fatality rate between the first and second waves, we analyzed programmatic COVID-19 data from Pune city, an epicenter of COVID-19 cases in India.

Method: The trends of cases incidence, time-to-death and case fatality rate (CFR) were analyzed. Poisson regression models adjusted for age and gender were used to determine the independent effect of pandemic waves on mortality.

A critical analysis of research methods and experimental models to study the load capacity and clinical behaviour of the root filled teeth.

The prognosis of root-filled teeth depends not only on a successful root canal treatment but also on the restorative prognosis. This critical review discusses the advantages and limitations of various methodologies used to assess the load capacity or clinical survivability of root-filled teeth and restorations. These methods include static loading, cyclic loading, finite element analysis and randomized clinical trials.

The Impact of the Auckland Cellulitis Pathway on Length of Hospital Stay, Mortality Readmission Rate, and Antibiotic Stewardship.

Background: The Dundee classification of cellulitis severity, previously shown to predict disease outcomes, provides an opportunity to improve the management of patients with cellulitis.

Methods: We developed and implemented a pathway to guide the management of adults with cellulitis based on their Dundee severity class, and measured its effect on patient outcomes. We compared the outcomes in patients admitted to Auckland City Hospital (ACH) between July 2014 and July 2015 (the baseline cohort) with those in patients admitted between June 2017 and June 2018 (the intervention cohort).

Promoter Proximal Pausing Limits Tumorous Growth Induced by the Yki Transcription Factor in .

Promoter proximal pausing (PPP) of RNA polymerase II has emerged as a crucial rate-limiting step in the regulation of gene expression. Regulation of PPP is brought about by complexes 7SK snRNP, P-TEFb (Cdk9/cycT), and the negative elongation factor (NELF), which are highly conserved from to humans. Here, we show that RNAi-mediated depletion of or of the 7SK snRNP complex or depletion of individual components of the NELF complex enhances Yki-driven growth, leading to neoplastic transformation of wing imaginal discs.

Genome-Wide Screen for Context-Dependent Tumor Suppressors Identified Using in Vivo Models for Neoplasia in .

Genetic approaches in have successfully identified many genes involved in regulation of growth control as well as genetic interactions relevant to the initiation and progression of cancer Here, we report on large-scale RNAi-based screens to identify potential tumor suppressor genes that interact with known cancer-drivers: the Epidermal Growth Factor Receptor and the Hippo pathway transcriptional cofactor Yorkie. These screens were designed to identify genes whose depletion drove tissue expressing EGFR or Yki from a state of benign overgrowth into neoplastic transformation We also report on an independent screen aimed to identify genes whose depletion suppressed formation of neoplastic tumors in an existing EGFR-dependent neoplasia model. Many of the positives identified here are known to be functional in growth control pathways.

Coordination polymer glass from a protic ionic liquid: proton conductivity and mechanical properties as an electrolyte.

High proton conducting electrolytes with mechanical moldability are a key material for energy devices. We propose an approach for creating a coordination polymer (CP) glass from a protic ionic liquid for a solid-state anhydrous proton conductor. A protic ionic liquid (dema)(HPO), with components which also act as bridging ligands, was applied to construct a CP glass (dema)[Zn(HPO)(HPO)].

A New Dimension for Coordination Polymers and Metal-Organic Frameworks: Towards Functional Glasses and Liquids.

There are two categories of coordination polymers (CPs): inorganic CPs (i-CPs) and organic ligand bridged CPs (o-CPs). Based on the successful crystal engineering of CPs, we here propose noncrystalline states and functionalities as a new research direction for CPs. Control over the liquid or glassy states in materials is essential to obtain specific properties and functions.

A Dual-Ligand Porous Coordination Polymer Chemiresistor with Modulated Conductivity and Porosity.

Single-ligand-based electronically conductive porous coordination polymers/metal-organic frameworks (EC-PCPs/MOFs) fail to meet the requirements of numerous electronic applications owing to their limited tunability in terms of both conductivity and topology. In this study, a new 2D π-conjugated EC-MOF containing copper units with mixed trigonal ligands was developed: Cu (HHTP)(THQ) (HHTP=2,3,6,7,10,11-hexahydrotriphenylene, THQ=tetrahydroxy-1,4-quinone). The modulated conductivity (σ≈2.

Crystal melting and glass formation in copper thiocyanate based coordination polymers.

Crystal melting and glass formation of coordination polymers (CPs) and metal-organic frameworks (MOFs) are rare thermal events. To expand the library of melting CP/MOFs, we utilized anti-crystal engineering in ionic liquids to construct CPs. A combination of Cu+ and 4,4'-bipyridin-1-ium derivatives afforded four melting CPs showing stable liquid and glassy states.

Universal dental adhesives: Current status, laboratory testing, and clinical performance.

Increasing demand for simplified and user-friendly adhesive systems has led to the development of a new class of adhesives termed as Universal Adhesives (UAs). The term "Universal" reflects manufacturers' claims that these adhesives can be applied with any adhesion strategy and offer the versatility of use with a variety of direct and indirect restorative materials. The aim of this review was to synthesize the literature regarding the current status of UAs, their adhesion potential to various substrates and their performance in different restorative situations.

Author Correction: Chemical Adsorption and Physical Confinement of Polysulfides with the Janus-faced Interlayer for High-performance Lithium-Sulfur Batteries.

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.

Influence of 2 caries-detecting devices on clinical decision making and lesion depth for suspicious occlusal lesions: A randomized trial from The National Dental Practice-Based Research Network.

Background: A suspicious occlusal carious lesion (SOCL) can be defined as a lesion with no cavitation and no radiographic radiolucency but for which caries is suspected. The authors evaluated whether using a device changed the percentage of SOCLs that were opened surgically and, among those SOCLs that were opened, the proportion that had penetrated into dentin.

Methods: Eighty-two dentists participated.

Digital versus conventional impressions for full-coverage restorations: A systematic review and meta-analysis.

Background: The primary objective of this systematic review was to investigate the survival of full-coverage restorations fabricated by using digital impressions (DIs) versus that of those fabricated by using conventional impressions. The authors also compared secondary outcomes of marginal and internal fit and occlusal and interproximal contacts.

Types Of Studies Reviewed: The authors conducted a systematic literature search in multiple databases to identify clinical trials with no restrictions by publication type, date, or language.

Chemical Adsorption and Physical Confinement of Polysulfides with the Janus-faced Interlayer for High-performance Lithium-Sulfur Batteries.

We design the Janus-like interlayer with two different functional faces for suppressing the shuttle of soluble lithium polysulfides (LPSs) in lithium-sulfur batteries (LSBs). At the front face, the conductive functionalized carbon fiber paper (f-CFP) having oxygen-containing groups i.e.

A proton-hopping charge storage mechanism of ionic one-dimensional coordination polymers for high-performance supercapacitors.

A proton-conducting coordination polymer of anionic one-dimensional (1D) chains of Zn phosphate and protonated imidazole with the formula of [Zn(HPO)(HPO)](ImH) has been used as a novel supercapacitor material in aqueous electrolytes. This material stores charges via a proton-hopping mechanism.

Synthesis of Oligodiacetylene Derivatives from Flexible Porous Coordination Frameworks.

Oligodiacetylenes (ODAs) with alternating ene-yne conjugated structure are significant materials for optical and electronic properties. Due to the low solubility of ODAs in common solvents, the synthetic approaches are limited. Here we disclose a new synthetic approach of ODAs without a side alkyl chain using a porous coordination polymer (PCP) as a sacrificial template.