Splenic and lymph nodal involvement in sarcoidosis mimicking lymphoma on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography.

Sarcoidosis is a multisystemic disease presenting with well-defined, bilateral, symmetric hilar and right paratracheal lymph node enlargement. Recently, fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (F-18 FDG PET/CT) has been used to stage and detect occult site of active inflammation in sarcoidosis. F-18 FDG PET/CT has become a cornerstone imaging modality in the modern lymphoma management, which can present with generalized lymphadenopathy including mediastinal.

Ocular sarcoidosis: does (18)F-FDG PET/CT have any role?

Sarcoidosis is a multisystemic disease, which may affect almost any organ including the eyes. Recently, F-FDG PET/CT has proved to be a very useful molecular imaging method allowing to obtain a complete morphofunctional cartography of active inflammatory sites and to assess treatment response in patients with sarcoidosis. We report 2 cases of sarcoidosis where F-FDG PET/CT showed intense FDG uptake in the eye globes along with multiple enlarged mediastinal lymph nodes suggestive of active sarcoidosis with ocular involvement.

Low serum PON1 activity: an independent risk factor for coronary artery disease in North-West Indian type 2 diabetics.

The paraoxonase (PON1) gene polymorphisms are known to affect the PON1 activity and coronary artery disease (CAD) risk. Studies done so far have given conflicting results. In the present study, we determined the role of PON1 genetic variants and PON1 activity in the development of CAD in North-West Indian Punjabis, a distinct ethnic group, having high incidence of both CAD and type 2 diabetes.

Role of gastric bypass in patients with unresectable advanced carcinoma of stomach.

Context: Role of bypass as a palliative surgery for advanced gastric cancer remains controversial.

Aims: To determine the role of bypass in advanced gastric cancer in comparision to resection as gold standard.

Design: Hospital-based retrospective outcome as study.

Role of gastric bypass in patients with unresectable advanced carcinoma of stomach.

Context: Role of bypass as a palliative surgery for advanced gastric cancer remains controversial.

Aims: To determine the role of bypass in advanced gastric cancer in comparision to resection as gold standard.

Design: Hospital based retrospective outcome study

Methods: Patients were divided into three groups: group I (gastric resection), group II (bypass) and group III (exploratory laparotomy alone).