CoRe study: COVID-19 and remdesivir: An insight into the current health planning and policy.

Introduction: The ongoing coronavirus disease-2019 (COVID-19) pandemic has witnessed rampant use of the repurposed drug, remdesivir, despite its conflicting evidence and rapidly changing guidelines.

Methods: A cross-sectional, country-wide, questionnaire-based, electronic survey was conducted among the healthcare professionals involved in COVID-19 management from April 18 to May 18, 2021.

Results: Out of 231 responses, 185 were included.

A Comparison of the Efficacy of Adjuvant Parenteral Methylprednisolone and Dexamethasone in Reducing Covid-19 Disease Severity and Mortality among the Moderate to Critical Patients -A Retrospective Study.

Unlabelled: The progression of the severity of COVID-19 caused by the SARS-Cov-2 virus is through an exaggerated host immune response called the cytokine storm. Corticosteroids can reduce this storm through their anti-inflammatory action, thus preventing lung damage. However the efficacy and side effect profile of the two commonly used corticosteroids- dexamethasone and methylprednisolone against COVID-19 have to be compared, to enable the selection of the appropriate drug with better outcomes.

Study Correlating Neutrophil-Lymphocyte Ratio with Clinical Staging in Mucormycosis Patients.

Unlabelled: Rhino-orbital mucormycosis is an aggressive fungal opportunistic infection of the immune-compromised, debilitated patients. The presence of neutrophilia and lymphocytopenia in patients affected with mucormycosis have been reported. Not much study has been done to establish the ratio of neutrophil to lymphocyte as a possible indicator for the severity of Rhino-orbital mucormycosis which is clinical staged.

Clinical Profile of Central Nervous System Involvement in Patients with Rhino Orbital Cerebral Mucormycosis.

Unlabelled: Mucormycosis is life threatening fungal infection that occurs in immunocompromised patients. Patients at risk are those with poorly controlled diabetes mellitus, immunosuppressed patients such as those undergoing treatment for hematological cancer or recipients of solid organ and hematopoietic stem cell transplantation. COVID 19 infection is known to produce a state of hyper inflammation with release of various cytokines this state of immune dysfunction is associated with development of opportunistic infections, of which Mucormycosis is on the rise currently.

HyPE study: hydroxychloroquine prophylaxis-related adverse events' analysis among healthcare workers during COVID-19 pandemic: a rising public health concern.

Background: The rising burden of Coronavirus disease (COVID-19) has led to the mass use of hydroxychloroquine by healthcare workers (HCWs). Adverse event profile of this drug when used as prophylaxis is not well known in the literature.

Methods: A retrospective, cross-sectional study was conducted across the country using semi-structured web-based questionnaire among COVID-19 negative and asymptomatic healthcare workers, taking hydroxychloroquine prophylaxis.

HIV Associated Sensory Neuropathy.

Background: In the era of highly active antiretroviral therapy, sensory neuropathies have increased in prevalence. We have documented the frequency and profile of the two most common forms of sensory neuropathies associated with Human Immunodeficiency Virus (HIV) infection and looked into clinicoelectrophysiological correlates to differentiate the two entities.

Methods: The study population comprised of all consecutive patients detected to be HIV positive and attending the Neurology outpatient department (from March 2011 to March 2012) who were aged ≥ 18 years and were able to give informed consent.