Patient Consent Management by a Purpose-Based Consent Model for Electronic Health Record Based on Blockchain Technology.

Objectives: Currently, patients' consent is essential to use their medical records for various purposes; however, most people give their consent using paper forms and have no control over it. Healthcare organizations also have difficulties in dealing with patient consent. The objective of this research is to develop a system for patients to manage their consent flexibly and for healthcare organizations to obtain patient consent efficiently for a variety of purposes.

Application of Blockchain to Maintaining Patient Records in Electronic Health Record for Enhanced Privacy, Scalability, and Availability.

Objectives: Electronic Health Record (EHR) systems are increasingly used as an effective method to share patients' records among different hospitals. However, it is still a challenge to access scattered patient data through multiple EHRs. Our goal is to build a system to access patient records easily among EHRs without relying on a centralized supervisory system.

Classification of Elastic and Collagen Fibers in H&E Stained Hyperspectral Images.

This study investigates the classification performance of elastic and collagen fibers using H&E stained hyperspectral images. As many as 1200 sample pixels were trained by using Linear discriminant analysis (LDA) and support vector machine (SVM) methods for reduction and classification. The classification result both using LDA and SVM show that H&E stained hyperspectral images performed better classification than H&E stained RGB image by comparing the classification of EVG stained images visually and quantitatively.

Secure biometric image sensor and authentication scheme based on compressed sensing.

It is important to ensure the security of biometric authentication information, because its leakage causes serious risks, such as replay attacks using the stolen biometric data, and also because it is almost impossible to replace raw biometric information. In this paper, we propose a secure biometric authentication scheme that protects such information by employing an optical data ciphering technique based on compressed sensing. The proposed scheme is based on two-factor authentication, the biometric information being supplemented by secret information that is used as a random seed for a cipher key.

Referenceless image quality evaluation for whole slide imaging.

Objective: The image quality in whole slide imaging (WSI) is one of the most important issues for the practical use of WSI scanners. In this paper, we proposed an image quality evaluation method for scanned slide images in which no reference image is required.

Methods: While most of the conventional methods for no-reference evaluation only deal with one image degradation at a time, the proposed method is capable of assessing both blur and noise by using an evaluation index which is calculated using the sharpness and noise information of the images in a given training data set by linear regression analysis.

Hybrid-resolution multispectral imaging using color filter array.

Hybrid-resolution multispectral imaging is a framework to acquire multispectral images through a reconstruction procedure using two types of measurement data with different spatial and spectral resolutions. In this paper, we propose a new method for such a framework on the basis of a full-resolution RGB image and the data obtained from an image sensor with a multispectral filter array (MSFA). In the proposed method, a small region of each image band is reconstructed as a linear combination of RGB images, where the weighting coefficients are determined using MSFA data.

Multispectral image enhancement for effective visualization.

Color enhancement of multispectral images is useful to visualize the image's spectral features. Previously, a color enhancement method, which enhances the feature of a specified spectral band without changing the average color distribution, was proposed. However, sometimes the enhanced features are indiscernible or invisible, especially when the enhanced spectrum lies outside the visible range.

Known plaintext attack on double random phase encoding using fingerprint as key and a method for avoiding the attack.

We have shown that the application of double random phase encoding (DRPE) to biometrics enables the use of biometrics as cipher keys for binary data encryption. However, DRPE is reported to be vulnerable to known-plaintext attacks (KPAs) using a phase recovery algorithm. In this study, we investigated the vulnerability of DRPE using fingerprints as cipher keys to the KPAs.

Feasibility study of near-infrared fluorescence tomography using a positron emission tomograph equipped with depth-of-interaction PET detectors.

We are currently developing an imaging system that combines simultaneous positron emission tomography (PET) with near-infrared (NIR) optical tomography, thus supporting two different types of molecular imaging. For this system, we are considering whether to use depth of interaction (DOI) PET detectors as simultaneous detectors of gamma rays and NIR light by changing the original upper reflectors to dichroic mirrors. The DOI-PET detector has very low spatial resolution for NIR light compared to the charge-coupled device cameras that are normally used.

Piecewise Wiener estimation for reconstruction of spectral reflectance image by multipoint spectral measurements.

This study proposes a piecewise Wiener estimation method to reconstruct a spectral reflectance image from a three-band image by multipoint spectral information collected simultaneously with image acquisition. A three-band image is divided into several blocks and the spectral estimation is carried out using the Wiener estimation matrix assigned to each block. Each Wiener estimation matrix is constructed on the basis of spectral measurement data.

Extraction of acne lesion in acne patients from multispectral images.

In acne treatment, it is important to accurately evaluate the severity of Acne. The acne should be classified into several skin lesions including comedo, reddish papule, pustule, and scar. However, in some cases, a visual detection from RGB image maybe difficult for the proper evaluation of acne skin lesions.

Color reproduction from low-SNR multispectral images using spatio-spectral Wiener estimation.

It is possible to capture images with high-fidelity color by using a spectrum-based color image reproduction method that estimates the spectral information of objects from a multispectral image along with information from illumination. When multispectral images do not have a sufficient signal-to-noise ratio (SNR), the accuracy of the spectral and color estimation will be reduced. To improve color estimation accuracy, this paper proposes a spatio-spectral Wiener estimation, which uses spatial correlation as well as spectral correlation.

Maximum a posteriori estimation of spectral reflectance from color image and multipoint spectral measurements.

Accurate color image reproduction under arbitrary illumination can be realized if the spectral reflectance functions in a scene are obtained. Although multispectral imaging is one of the promising methods to obtain the reflectance of a scene, it is expected to reduce the number of color channels without significant loss of accuracy. This paper presents what we believe to be a new method for estimating spectral reflectance functions from color image and multipoint spectral measurements based on maximum a posteriori (MAP) estimation.

Experimental evaluation of fingerprint verification system based on double random phase encoding.

We proposed a smart card holder authentication system that combines fingerprint verification with PIN verification by applying a double random phase encoding scheme. In this system, the probability of accurate verification of an authorized individual reduces when the fingerprint is shifted significantly. In this paper, a review of the proposed system is presented and preprocessing for improving the false rejection rate is proposed.

Digital staining for multispectral images of pathological tissue specimens based on combined classification of spectral transmittance.

In this study, the digital transformation (digital staining) of the 16-band multispectral image of a hematoxylin and eosin (HE) stained pathological specimen to its Masson's trichrome (MT) stained counterpart is addressed. The digital staining procedure involves the classification of the various H&E-stained tissue components and then the transformation of their transmittance spectra to their equivalent MT-stained transmittance configurations. Combination of transmittance classifiers were designed to classify the various tissue components found in the multispectral images of an HE-stained specimen, e.

Transaxial system models for jPET-D4 image reconstruction.

A high-performance brain PET scanner, jPET-D4, which provides four-layer depth-of-interaction (DOI) information, is being developed to achieve not only high spatial resolution, but also high scanner sensitivity. One technical issue to be dealt with is the data dimensions which increase in proportion to the square of the number of DOI layers. It is, therefore, difficult to apply algebraic or statistical image reconstruction methods directly to DOI-PET, though they improve image quality through accurate system modelling.

Appearance of enhanced tissue features in narrow-band endoscopic imaging.

This study was performed to examine the usefulness of medical endoscopic imaging utilizing narrow-band illumination. The contrast between the vascular pattern and the adjacent mucosa of the underside of the human tongue was measured using five narrow-band illuminations and three broadband illuminations. The results demonstrate that the pathological features of a vascular pattern are dependent on the center wavelength and the bandwidth of illumination.

Multiple-discriminant analysis for light-scattering spectroscopy and imaging of two-layered tissue phantoms.

We propose a new method for enhancing the sensitivity of the reflectance spectrum to the scattering feature of the superficial tissue layer. This method is based on multiple-discriminant analysis in the eigensubspace of the spectrum. Considering the application of scattering imaging, we evaluated this method by performing multispectral imaging of two-layered tissue phantoms.

Fast determination method of cerebral metabolic rate images of glucose using dynamic PET data.

Measurement of the rate constant parameters of the tracer 18F-FDG, used with positron emission tomography (PET) to determine the cerebral metabolic rate of glucose (CMRGlc), can provide a clear understanding of the physiological processes in the human brain. At present, the methods that are widely used to obtain CMRGlc, such as nonlinear least squares (NLS), first require the reconstruction of a time sequence of images. The reconstruction of these images requires a large amount of computation, especially in 3D Depth-of Interaction PET (DOI-PET), and the nonlinear based methods also require a large amount of computation.

[Algebraic 2D PET image reconstruction using depth-of-interaction information].

Recently a high-performance PET scanner, which measures depth-of-interaction (DOI) information, is being developed for molecular imaging. DOI measurement of multi-layered thin crystals can improve spatial resolution and scanner sensitivity simultaneously. In this paper, we apply an algebraic image reconstruction method to 2-dimensional (2D) DOI-PET scanners using accurate system modeling, in order to evaluate the effects of using DOI information on PET image quality.

Nonlinear estimation of spectral reflectance based on Gaussian mixture distribution for color image reproduction.

Nonlinear estimation method of spectral reflectance from camera responses is proposed. The proposed method minimizes the mean square error of spectral reflectance when the reflectance can be regarded as a random sequence of Gaussian mixture distribution. In computer simulations, 168 samples of spectral reflectance from a color chart are estimated from their image signals obtained by three- and six-band cameras.