A study on the association of rs7950273 polymorphism in the PDGFD with ischaemic stroke in the Chinese Han population.

Background: The association between the platelet-derived growth factor D (PDGFD) gene and atherosclerosis has been widely proven, whereas the relationship between the PDGFD gene and ischaemic stroke remains unconfirmed.

Aim: A case-control study was performed to further evaluate the association of the C → G mutation of rs7950273 in the PDGFD gene with ischaemic stroke (IS) in a Chinese Han population.

Subjects And Methods: This study recruited 3033 cases and 2807 controls from general hospitals in the southern, central and northern areas of China.