Publications by authors named "Naemi Reuscher"
Article Synopsis
- The study focuses on the regulatory volume decrease (RVD) mechanism in human keratinocytes under hypotonic stress, highlighting the role of the LRRC8 volume-regulated anion channel (VRAC) and the influence of calcium (Ca) levels.
- Researchers explored whether the TRPV4 ion channel is crucial for Ca influx during RVD in keratinocytes by using specific inhibitors and CRISPR/Cas9 knockout techniques.
- Findings showed that TRPV4 is not necessary for the response to hypotonic stress as both Ca influx and RVD processes remained unaffected without TRPV4, suggesting other unidentified Ca channels are involved in this cellular response.
