Overall survival with cisplatin and 5-fluorouracil neoadjuvant treatment in patients with esophageal cancer: single-center experience.

Background: The survival benefit of neoadjuvant chemotherapy in patients undergoing surgery for esophageal cancer is unclear.

Patients And Methods: We retrospectively identified 37 patients with resectable esophageal squamous cell carcinoma or adenocarcinoma, who prior to surgery received 2 cycles of chemotherapy, consisting of cisplatin 80 mg/m(2) as 3-h intravenous infusion on day 1 followed by 5-fluorouracil 1,000 mg/m(2) as 96-h continuous infusion on days 1-4, separated by a 3-week interval. Surgery was performed 3-5 weeks after the start of the second cycle of chemotherapy.

[Acute rectal bleeding from malignant stromal tumor].

Stromal tumors of the rectum are rare. The most common symptoms are rectal bleeding, pain, constipation and obstruction. A case report of a 61 years old female admitted with acute bleeding due to malignant stromal tumor of the rectum is described.