Publications by authors named "Nadya Helena Alves-Santos"

Background: The consumption of ultra-processed foods (UPFs) has increased worldwide, including among children. Maternal schooling has been associated with children's UPF consumption. The present study examined the interaction between maternal schooling and child age in the association with UPF consumption in Brazilian children <5 years.

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Objective: To evaluate the association between the dietary patterns (DPs) of pregnant women with GDM (gestational diabetes ) and the birth weight (BW) of the infants.

Methods: Cross-sectional study with 187 adult pregnant women with GDM attended at a maternity in Rio de Janeiro from 2011 to 2014. Dietary intake was assessed in the third trimester using a semiquantitative food frequency questionnaire (FFQ).

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  • The study aimed to assess food poverty among Brazilian children by analyzing dietary data and socio-economic factors, using a UNICEF classification for food poverty levels.
  • Results showed that 32.5% of children faced moderate food poverty and 6.0% experienced severe food poverty, particularly among those with less-educated and lower-income mothers/caregivers.
  • The most commonly consumed foods among children in severe food poverty were dairy products, grains, and ultra-processed foods, indicating a concerning dietary pattern.
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  • - This study analyzes the nutrition transition of Brazilian children under 5 from 2006 to 2019, focusing on micronutrient deficiencies, stunting, excessive weight, and breastfeeding practices using data from two national surveys.
  • - Significant improvements were noted in anemia and vitamin A deficiency rates, while stunting remained steady and excessive weight increased during this period, with breastfeeding practices also seeing positive trends.
  • - By 2019, many children achieved minimum dietary diversity, but high consumption of ultra-processed foods and low intake of fruits and vegetables were concerning, highlighting ongoing disparities impacted by geographical and maternal factors.
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  • - The study examined the prevalence of minimum dietary diversity (MDD) and ultra-processed food consumption among 4,354 Brazilian children aged 6-23 months, considering factors like sociodemographic variables and regional differences.
  • - MDD was found in 63.4% of the children, with lower rates in regions like the North (54.8%) and among those with less educated caregivers or facing food insecurity, while 80.5% consumed ultra-processed foods, particularly in the North (84.5%).
  • - Only 8.4% of children achieved MDD without ultra-processed foods, highlighting dietary challenges among vulnerable populations and emphasizing the need for improved nutrition policies for infants in Brazil.
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Persistent organic pollutants (POPs) are compounds that are recalcitrant and ubiquitous that bioaccumulate in human milk (HM) and can impact infant growth and development. We explore the association between POP concentration in HM at 2-50 days postpartum and infant growth and development trajectory throughout the first year of life. A cohort of 68 healthy adult Brazilian women and their infants were followed from 28 to 35 gestational weeks to 12 months postpartum.

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  • The study analyzed factors related to anemia and vitamin A deficiency in 7,716 Brazilian children aged 6-59 months, revealing significant associations with socio-economic and demographic factors like maternal education and age.
  • Children aged 6-23 months were notably affected, especially if their mothers had less education or were younger, while regional disparities were evident with higher prevalence in the North.
  • The research highlights the importance of tailored public health policies to address nutritional deficiencies, particularly in vulnerable groups, and suggests that certain dietary habits and breastfeeding practices can influence these health outcomes.
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  • Malnutrition is a significant global health issue, and this study focused on its prevalence among mother-child pairs in Brazil for children under 5 years old, comparing data from 2006 and 2019.* -
  • The findings revealed that in 2019, 58.2% of mothers and 9.7% of children were overweight, with rising rates of overweight in mother-child dyads and an increase in the double burden of malnutrition over the years.* -
  • Vulnerability to malnutrition was higher in dyads with lower maternal education, older mothers, and those from Southern Brazil, highlighting the need for targeted interventions in these populations.*
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  • The study aimed to analyze the rates of cross-breastfeeding, human milk donation to milk banks, and the reception of milk from these banks among Brazilian mothers.
  • Using data from the Brazilian National Survey on Child Nutrition (ENANI-2019), researchers focused on 5,831 mothers of children under two years who had breastfed, finding that 21.1% practiced cross-breastfeeding.
  • Although 4.8% of mothers donated milk and 3.6% reported their children received donated milk, cross-breastfeeding poses health risks, highlighting the need for discussion around these practices in Brazil and globally.
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  • The study analyzes breastfeeding trends in Brazil from 1996 to 2019 using data from national surveys to inform public health policies.
  • Key indicators assessed include early initiation of breastfeeding, exclusive breastfeeding in infants under 6 months, and continued breastfeeding rates at 1 and 2 years of age, showing significant improvements over the years.
  • However, the research highlights that certain regions in Brazil, particularly the South and Southeast, will need substantial increases in prevalence to meet the WHO/UNICEF breastfeeding targets by 2030.
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This study compared the distribution of stunting and height-for-age (HAZ) Z-scores among age groups in data from the Brazilian National Survey on Demography and Health of Women and Children (PNDS 2006) and the Brazilian National Survey on Child Nutrition (ENANI-2019). The final sample comprised 4,408 and 14,553 children < 59 months of age in the PNDS 2006 and ENANI-2019, respectively. Children with HAZ scores < -2 according to the World Health Organization (WHO) growth standard were classified as stunted.

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  • The study examined the use of micronutrient supplements among Brazilian children aged 6-59 months, analyzing data from the Brazilian National Survey on Child Nutrition (ENANI-2019) with a sample of 12,598 children.
  • Findings revealed that 54.2% of children were using micronutrient supplements, with the highest usage (80.2%) reported in the North Region and among younger children aged 6-23 months (69.5%).
  • The prevalence of specific supplements included 14.6% for iron, 23.3% for vitamin A, and 24.3% for multivitamins, highlighting the need for informed public policies to address micronutrient
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The National Wealth Score (IEN) is a synthetic household index that assesses socioeconomic conditions. This study aims to present the methods used to update the IEN using data from the Brazilian National Survey on Child Nutrition (ENANI-2019). The following items were included: the education level of the mother or caregiver of the child; the number of bedrooms and bathrooms, TV sets, and cars in the household; and the presence of a radio, refrigerator or freezer, washing machine, microwave oven, telephone line, computers, air conditioner, media player devices, cable or satellite TV, cell phone ownership and type of service, cell phone internet, and internet at the household.

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To analyse the association of socio-demographic and health factors with vitamin D insufficiency and 25-hydroxyvitamin D (25(OH)D) concentration in Brazilian children aged 6-59 months. Data from 8145 children from the Brazilian National Survey on Child Nutrition (ENANI-2019) were analysed. The serum concentration of 25(OHD)D was measured using a chemiluminescent immunoassay.

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Persistent organic pollutants (POPs) are toxic chemical compounds that can bioaccumulate, adhere to lipid matrices, and affect human health. This study aimed to investigate the association between maternal pre-pregnancy overweight/obesity and dietary intake during pregnancy and POP concentrations in the human milk of women from Rio de Janeiro, Brazil. One hundred and forty-seven women were followed from the third trimester of pregnancy until 119 days postpartum, and 77 human milk samples were analyzed between 2 and 119 days postpartum.

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This manuscript aims to describe the methodological, operational, and quality control aspects of the assessment of dietary intake in children under five years of age participating in the Brazilian National Survey on Child Nutrition (ENANI-2019), a household survey in a probability sample of Brazilian households. Two instruments were developed to assess child feeding practices - a structured, current status-type questionnaire and a 24-hour dietary recall (24HR), both installed in a mobile data collection device used by previously trained interviewers. A Photographic Manual for Quantification of Children's Dietary Intake was specifically developed for and used in the survey as a support aid to identify and quantify foods reported in the 24HR.

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This article aims to present methodological aspects on the collection, analyses, coverage, challenges, and the lessons learned from laboratory assessment of micronutrients on the Brazilian National Survey on Child Nutrition (ENANI-2019). This is a household survey on a probability sample of children under five years of age from 123 Brazilian municipalities in all 26 states and the Federal District. Blood samples were drawn by venipuncture at the homes of children 6 to 59 months of age.

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This article aims to present general methodological aspects of the Brazilian National Survey on Child Nutrition (ENANI-2019), from the conception of the study design to details of the data collection. This is a household-based population survey with a sample calculated at 15,000 households to identify children under five years of age, conducted in 123 municipalities in Brazil's 26 states and the Federal District. ENANI-2019 includes data on breastfeeding and dietary intake; anthropometric nutritional status of all children and their biological mothers; and nutritional status concerning the following micronutrients: iron (hemoglobin and ferritin), zinc, selenium, and vitamins A, B1, B6, B12, D, E, and folic acid of children from 6 to 59 months of age.

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The article presents methodological aspects of anthropometric assessment of nutritional status in children under five years of age and their biological mothers. It discusses the strategies used for training and data collection in the Brazilian National Survey on Child Nutrition (ENANI-2019). ENANI-2019 is a population-based household survey conducted in 123 municipalities in Brazil's 26 states and the Federal District.

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The article describes methodological aspects in defining the study population, sampling plan, and sample weigthing and calibration of effective sample of the Brazilian National Survey on Child Nutrition (ENANI-2019). This population-based household survey assessed breastfeeding and dietary intake, anthropometric assessment of nutritional status, and micronutrient deficiencies by blood biomarkers in children under five years of age. The data were obtained with a probability sample, with stratification by the five geographic regions in the country and clustering by census enumeration areas (CEAs).

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Purpose: Little is known about the effects of leptin and leptin receptor polymorphisms on lipid changes during pregnancy. The aims of this study were to evaluate the associations between the single nucleotide polymorphisms (SNPs) of leptin and leptin receptor genes and the lipid concentrations during pregnancy; and to test whether dietary intake is a mediator in these associations.

Methods: A prospective cohort of 154 pregnant women was followed up in Rio de Janeiro, Brazil during the following gestational periods: 5-13th, 20-26th and 30-36th weeks.

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Background: Dietary intake may be associated with neonatal outcomes, yet little is known about the influence of prepregnancy dietary pattern (DP).

Objectives: To evaluate the association between prepregnancy DPs and perinatal outcomes.

Design: Prospective cohort study during pregnancy (baseline between 5 and 13 gestational week and three follow-up visits: 20 to 26 gestational weeks, 30 to 36 gestational weeks, and 30 to 40 days postpartum, respectively).

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