Senecipyrrolidine, an unusual pyrrolidine alkaloid isolated from (Desf.) Pelser (Asteraceae).

Alkaloids and phenolic compounds are among the most biologically active natural products from the / genera (Asteraceae). To isolate original natural products directly from crude polar extracts, centrifugal partition chromatography (CPC) was used. Previously, we reported the phytochemical study of (syn.

Fast counter current chromatography of n-butanolic fraction from Senecio giganteus (Asteraceae).

Phenolic derivatives such as quinones, acid-phenols and flavonoids were successfully isolated from a n-butanolic fraction of Senecio giganteus Desf. (Asteraceae) flowers, namely jacaranone (1), 3a-hydroxy-3,3a,7,7a-tetrahydrobenzofuran-2,6-dione (2), chlorogenic acid (3), hyperoside (4), quercetin 3-O-beta-D-robinobioside (5), isorhamnetin-3-O-beta-D-glucuronide (6), quercetin-3-O-beta-D-glucuronide (7), and isorhamnetin-3-O-beta-D-glucuronide-6"-methyl ester (8). These compounds were purified through either classical polyamide filtration followed by fractionation on Si gel, or through fast centrifugal partition chromatography (FCPC).