Publications by authors named "Nadja Utz"
Article Synopsis
- - Transcriptional interference and read-through are key mechanisms in gene silencing and the establishment of DNA methylation, which impacts gene expression and can contribute to disease.
- - Researchers developed a cell culture system to investigate how transcriptional read-through influences gene repression and DNA methylation at specific human gene promoters.
- - Inducing transcriptional read-through led to consistent gene repression, regardless of promoter type, but did not result in DNA methylation, suggesting additional factors beyond transcription and DNA methyltransferases are necessary for methylation to occur.
View Article and Find Full Text PDF