Publications by authors named "Nadja Schughart"
Background: Humanized murine models comprise a new tool to analyze novel therapeutic strategies for allergic diseases of the intestine.
Objective: In this study we developed a human PBMC-engrafted murine model of allergen-driven gut inflammation and analyzed the underlying immunologic mechanisms.
Methods: Nonobese diabetic (NOD)-scid-γc(-/-) mice were injected intraperitoneally with human PBMCs from allergic donors together with the respective allergen or not.