Publications by authors named "Nadiyah Alshehri"

Article Synopsis
  • - The study investigated how COVID-19 affected influenza prevalence in Saudi Arabia, comparing data from before (2017-2019) and during the pandemic (2020-2021) to assess the impact of intervention measures.
  • - A total of 5,238 influenza cases were identified, revealing a significant decline during the pandemic years, with cases dropping from around 2% yearly pre-COVID-19 to 0.63% and 1.27% in 2020 and 2021, respectively.
  • - The findings indicated that older individuals were more likely to be infected with influenza during the pandemic years, suggesting a shift in the demographic profile of patients compared to pre-pandemic times.
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Background: Despite insufficient evidence, vitamin D has been used as adjunctive therapy in critically ill patients with COVID-19. This study evaluates the effectiveness and safety of vitamin D as an adjunctive therapy in critically ill COVID-19 patients.

Methods: A multicenter retrospective cohort study that included all adult COVID-19 patients admitted to the intensive care units (ICUs) between March 2020 and July 2021.

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Background: Vancomycin is a commonly used antibiotic in critically ill patients for various indications. Critical illness imposes pharmacokinetic-pharmacodynamics challenges, which makes optimizing vancomycin in this population cumbersome. Data are scarce on the clinical impact of time to therapeutic trough levels of vancomycin in critically ill patients.

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Background: Vancomycin is one of the most common therapeutic agents for treating gram-positive infections, particularly in critically ill patients. The aim of this study was to identify factors associated with initial therapeutic vancomycin trough levels and mortality in a tertiary-care intensive care unit (ICU).

Methods: This retrospective study evaluated 301 adult ICU patients admitted to King Abdulaziz Medical City in Riyadh between October 1, 2017 and December 31, 2018 with confirmed gram-positive infections and received intravenous vancomycin.

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