Experience with Dopamine Agonists in the Treatment of Prolactinomas.

The article is devoted to the conservative treatment of hyperprolactinemia of tumor origin. Cabergoline is considered as an effective treatment not only for microadenomas but also for large pituitary tumors which is illustrated by the clinical case of the patient P. The most important effects of cabergoline demonstrated in this clinical case are reduction in the size of the adenoma from macro to micro, reverse development of chiasmal syndrome with restoration of visual functions, achievement and maintenance of the target level of prolactin.

CLINICAL AND IMMUNOLOGICAL ASPECTS OF VERIFICATION OF LATENT AUTOIMMUNE DIABETES IN ADULTS AT EARLY STAGES OF DISEASE MANIFESTATION.

Objective: The aim: To establish diagnostic markers of LADA at the stage of manifestation based on the analysis of clinical and anamnestic data, the results of immunological examination of patients with different types of DM.

Patients And Methods: Materials and methods: Study included 121 patients with LADA (1st (main) group), 60 patients with type 1 DM (2nd group), 81 patients with type 2 DM (3d group). The examination included analysis of complaints, medical history, determination of anthropometric data, studies of the level of antibodies to glutamic acid decarboxylase (GAD ab), cytoplasmic antigen (ICA ab), tyrosine phosphatase (IA-2 ab).

General cardiovascular risk and functional indicators of the permanent atrial fibrillation.

Objective: Introduction: No doubt today that atrial fibrillation (AF) is associated with an increased risk of thromboembolic events. Simultaneously we did not find any investigation about the links between general cardiovascular risk (GCVR) and the frequency forms and functional parameters of the heart in patients with AF. The aim: To study the frequency forms and functional indices of the heart in patients with permanent AF in GCVR groups.